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Find the cheapest bus tickets from Santiago to Cusco

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Santiago to Cusco Buses

With Busbud, comparing and booking tickets for a bus from Santiago to Cusco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santiago to Cusco will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Cusco from Santiago, we help you find what you're looking for based on how much of a budget you have.

Stations & Stops

Need a bus leaving from Santiago? Your starting point is at Terminal Sur, Terrapuerto Los Heroes, San Borja, Pajaritos, Omnium, Terminal ETM, Cruce Colon, Antonio Bellet, Arturo Alessandri or Bellavista.

If you're onboard a bus traveling to Cusco, you can get hop off at Terminal Cruz Del Sur, Terminal Terrestre, Estacion Wanchaq or Cusco.

Santiago to Cusco Route Map

Santiago to Cusco Route Map

Frequently asked questions on the trip Santiago - Cusco

What are the departure and arrival stations when taking the bus from Santiago to Cusco?

Buses travelling between Santiago and Cusco leave from Terminal Sur or Terrapuerto Los Heroes and arrive at Terminal Cruz Del Sur, Terminal Terrestre, Estacion Wanchaq.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Santiago to Cusco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santiago to Cusco, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santiago to Cusco.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santiago to Cusco.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Santiago by bus?

If you are looking for the return bus journey, check out buses from Cusco to Santiago.

Popular Buses Connecting Santiago

Popular Buses Connecting Cusco

Popular routes in this country

Why choose Busbud?

The Best Way To Book Bus Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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