Bus from Santiago de Chile to Antofagasta: Tickets & Schedules

Next bus departures

Next departures for Santiago de Chile to Antofagasta on July 20
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AndimarBus
Terminal San Borja
Terminal de Buses Cardenal Carlos Oviedo Cavada)Cheapest
Cikbus ElitéBus
Terminal de Buses San Borja - San Francisco de Borja
Terminal AntofagastaFastest
Pluss ChileBus
San Borja
Terminal AntofagastaNo tags
Cikbus ElitéBus
Terminal de Buses San Borja - San Francisco de Borja
Terminal AntofagastaNo tags
Pullman San AndrésBus
Terminal San Borjas
Terminal Carlos Oviedo CavadaNo tags
Flixbus ChileBus
Terminal San Borja
Terminal de Buses Cardenal Carlos Oviedo Cavada)No tags
AndimarBus
Terminal San Borja
Terminal de Buses Cardenal Carlos Oviedo Cavada)No tags
Flixbus Chile + Andimar
Bus
Santiago (Los Libertadores)
Terminal de Buses Cardenal Carlos Oviedo Cavada)No tags

Last refresh of the prices: Today at 3:34 PM -04.

Get from Santiago de Chile to Antofagasta

This route is served by bus only

The journey takes about 18 hours 40 minutes, and with fares starting at just $49, it presents an excellent value for a comfortable ride.

48bus per day
18h 40mAverage Duration
1094 kmDistance
27kgCO₂ emissions

Frequently asked questions about travelling from Santiago de Chile to Antofagasta by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Santiago de Chile to Antofagasta?

    The cheapest bus tickets from Santiago de Chile to Antofagasta start from $49. The average price for this route is around $73. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Santiago de Chile to Antofagasta?

    The average bus travel time from Santiago de Chile to Antofagasta is 18h 40m, covering a distance of 1094 km. The quickest bus can get you there in 15h 40m and is operated by Pullman San Andres.

  3. Which bus companies service the Santiago de Chile to Antofagasta route?

    Several major bus companies operate on this route with 48 buses available per day, including services from Pluss Chile, Pullman San Andres, Cikbus Elité, Buses Andimar, FlixBus, Buses Evans.

  4. What are the earliest and latest departure times for the bus from Santiago de Chile to Antofagasta?

    The earliest bus departs from Santiago de Chile to Antofagasta at 6:15am. And the latest bus departs at 11:59pm.

  5. What are the CO₂ emissions for the bus trip from Santiago de Chile to Antofagasta?

    A bus trip from Santiago de Chile to Antofagasta generates an estimated 27.328149999999997 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Santiago de Chile to Antofagasta?

    According to Busbud customers, the highest-rated bus company on this route is Buses Andimar, with an average rating of 3.9 out of 5 stars based on 65 reviews.

  7. Which bus company has the best Wi-Fi from Santiago de Chile to Antofagasta?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Santiago de Chile to Antofagasta?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Santiago de Chile to Antofagasta?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pullman San Andres, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-17
$51
07-18
$58
Today
$58
07-20
$52
07-21
$46
07-22
$46
07-23
$46
07-24
$46
busbud logoThe cheapest trip from Santiago de Chile to Antofagasta was searched and found on Jul 21, 2026 with a price of $46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago de Chile to Antofagasta, as early as possible.

You can expect to pay from $46 to $88 for a bus ticket from Santiago de Chile to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2026-07-21.

Usually Pullman San Andres, Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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