How much is the bus ticket from Santiago de Chile to Santa Cruz?

The cheapest coach tickets from Santiago de Chile to Santa Cruz start from £5. The average price for this route is around £6. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Santiago de Chile to Santa Cruz?

The average bus journey time from Santiago de Chile to Santa Cruz is 2h 40m, covering a distance of 88 miles. The fastest bus can take you there in 2h 25m and is operated by Buses Andimar .

Which bus companies service the Santiago de Chile to Santa Cruz route?

Several major bus companies operate on this route with 43 buses available per day, including services from Buses Andimar , buses TranSantin , FlixBus , Buses Jet Sur .

What is the earliest and latest departure time for the bus from Santiago de Chile to Santa Cruz?

The earliest bus departs from Santiago de Chile to Santa Cruz at 05:30. And the latest bus departs at 21:14.

What are the CO₂ emissions for the bus trip from Santiago de Chile to Santa Cruz?

A bus journey from Santiago de Chile to Santa Cruz produces an estimated 3.528225 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Santiago de Chile to Santa Cruz?

According to Busbud customers, the highest-rated bus company on this route is buses TranSantin , with an average rating of 4.1 out of 5 stars based on 323 reviews.

Which company has the best Wi-Fi from Santiago de Chile to Santa Cruz?

Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Santiago de Chile to Santa Cruz?

According to Busbud traveller reviews, the most punctual bus company on this route is buses TranSantin , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Santiago de Chile to Santa Cruz?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin , with a cleanliness rating of 4.5 out of 5 stars.

Bus Santiago de Chile to Santa Cruz from £5 | Refundable Tickets

Next bus departures

Next departures from Santiago de Chile to Santa Cruz on 19 May
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	18:55	Terminal Sur	2h 40m	21:35	Terminal Santa Cruz	Cheapest
Bus	06:30	San Bernardo, Santiago (Cruce Colon)	2h 25m	08:55	Terminal de Buses Santa Cruz	Fastest
Bus	09:45	Terminal Sur	2h 40m	12:25	Terminal Santa Cruz	No tags
Bus	15:50	Terminal Sur	3h	18:50	Terminal Santa Cruz	No tags
Bus	09:14	San Bernardo, Santiago (Cruce Colon)	2h 25m	11:39	Terminal de Buses Santa Cruz	No tags

Last refresh of the prices: Yesterday at 23:25 -04.

Get from Santiago de Chile to Santa Cruz

This route is served by bus only

The journey takes about 2 hours 40 minutes, and with fares starting at just £5, it presents an excellent value for a comfortable ride.

43bus per day

2h 40mAverage duration

88 milesDistance

4kgCO₂ emissions

Where are the popular stops in Santiago de Chile and Santa Cruz?

Stops in Santiago de Chile

A
Terminal Sur
Santiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
Visit page
B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile
C
Terminal Los Héroes
Tucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
Visit page
D
Terminal ETM
Pdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
Visit page
E
Pajaritos
Av. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
Visit page
F
Rancagua
Estado 480, Rancagua, VI Región, Chile
Visit page

Stops in Santa Cruz

A
Terminal Santa Cruz
Av. Rafael Casanova 480, Santa Cruz, VI Región, Chile
Visit page

Compare bus companies

Buses Andimar

3.9/564 reviews

Staff4.3

Timeliness3.9

Cleanliness4.3

Wi‑Fi0.9

According to the reviews, customers had a great experience with comfortable bus seats and a very nice conductor. The service was on time as well. However, some passengers mentioned the need for more legroom and discomfort due to another passenger playing videos without headphones throughout the journey.

Andimar Santiago de Chile Santa Cruz recent customer reviews

Comfy headrest, but needed more legroom. One passenger played videos without headphones the entire journey 🙄

David H.

26 March 2024

I won’t use this service again it’s shocking

Jack C.

22 April 2025

Comfortable seats, very nice conductor, on time !!!

Philip Z.

14 January 2024

buses TranSantin

4.1/5323 reviews

Staff4.8

Timeliness4.3

Cleanliness4.5

Wi‑Fi1.7

Based on 323 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the Wi‑Fi. buses TranSantin ticket prices on this trip start at £5

Buses TranSantin Santiago de Chile Santa Cruz recent customer reviews

Dirty bus, arm rest was broken, seatbelt didn’t work properly, the toilet was dirty and really hot.

Isaac D.

9 January 2026

Easy to find. Left on time. Dealt with traffic situations to arrive as soon as practicable.

Paul O.

22 August 2025

FlixBus

3.5/512,662 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Buses Jet Sur

3.3/588 reviews

Staff4.5

Timeliness4.1

Cleanliness4.0

Wi‑Fi0.5

Based on 88 reviews, the company was rated 3.3 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi‑Fi. Buses Jet Sur ticket prices on this trip start at £7

Buses Jet Sur Santiago de Chile Santa Cruz recent customer reviews

The bus got me to my destination. The seat was uncomfortable, narrow with armrests a bit too high.

Terrence S.

21 March 2025

CL bus companies:FlixBus, Via Tac, Andesmar, CATA Internacional, Buses Andimar, buses TranSantin, ETM

Frequently asked questions about travelling by bus from Santiago de Chile to Santa Cruz, CL

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Santiago de Chile to Santa Cruz?
The cheapest coach tickets from Santiago de Chile to Santa Cruz start from £5. The average price for this route is around £6. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Santiago de Chile to Santa Cruz?
The average bus journey time from Santiago de Chile to Santa Cruz is 2h 40m, covering a distance of 88 miles. The fastest bus can take you there in 2h 25m and is operated by Buses Andimar.
Which bus companies service the Santiago de Chile to Santa Cruz route?
Several major bus companies operate on this route with 43 buses available per day, including services from Buses Andimar, buses TranSantin, FlixBus, Buses Jet Sur.
What is the earliest and latest departure time for the bus from Santiago de Chile to Santa Cruz?
The earliest bus departs from Santiago de Chile to Santa Cruz at 05:30. And the latest bus departs at 21:14.
What are the CO₂ emissions for the bus trip from Santiago de Chile to Santa Cruz?
A bus journey from Santiago de Chile to Santa Cruz produces an estimated 3.528225 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Santiago de Chile to Santa Cruz?
According to Busbud customers, the highest-rated bus company on this route is buses TranSantin, with an average rating of 4.1 out of 5 stars based on 323 reviews.
Which company has the best Wi-Fi from Santiago de Chile to Santa Cruz?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Santiago de Chile to Santa Cruz?
According to Busbud traveller reviews, the most punctual bus company on this route is buses TranSantin, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santiago de Chile to Santa Cruz?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

16/05

£5

17/05

£5

Today

£5

19/05

£5

20/05

£5

21/05

£5

22/05

£5

23/05

£5

The cheapest trip from Santiago de Chile to Santa Cruz, CL was searched and found on 16 May 2026 with a price of £5

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago de Chile to Santa Cruz, CL as early as possible.

You can expect to pay from £5 to £9 for a bus ticket from Santiago de Chile to Santa Cruz, CL based on the last 2 days. You can expect to find the cheapest price for the trip at £5, which is on 2026-05-19.

Usually Buses Andimar, Buses Jet Sur will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.