Find coaches from Fort Pierce to Panama City, US

Next departures

Next departures from Fort Pierce to Panama City on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Fort Pierce Bus Stop - Loves Gas Station
    		Panama City Beach StationCheapestFastest

    Last refresh of the prices: Last Friday at 11:33 PM EDT.

    Accepted payments

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    Get from Fort Pierce to Panama City

    This route is served by bus only

    The journey takes about 13 hours 5 minutes, and with fares starting at just US$121, it presents an excellent value for a comfortable ride.

    4bus per day
    13h 5mAverage duration
    608 kmDistance
    15kgCO₂ emissions

    Bus Fort Pierce to Panama City, US: Trip Overview

    Average ticket priceUS$123
    Average bus trip duration13h 5m
    Number of daily buses4
    Earliest bus departure01:55
    Distance608 km
    Latest bus departure20:30

    Fort Pierce to Panama City Bus

    Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Fort Pierce to Panama City.

    We make sure you can find a bus service from Fort Pierce to Panama City from the most reliable bus companies operating this trip.

    From cheap bus tickets to more luxurious buses travelling from Fort Pierce to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

    Frequently asked questions on the trip Fort Pierce - Panama City, US

    1. How much does a bus ticket from Fort Pierce to Panama City cost?

      The bus ticket price from Fort Pierce to Panama City starts at US$121. The best way to find cheap bus tickets from Fort Pierce to Panama City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the bus ride from Fort Pierce to Panama City?

      The average travel time between Fort Pierce and Panama City is around 13h 5m, although the fastest bus will take about 12h 50m. This is the time it takes to travel the 603 km that separates the two cities.

    3. How many daily bus connections are there between Fort Pierce and Panama City?

      The number of buses from Fort Pierce to Panama City can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Fort Pierce to Panama City by comparing and selecting the bus that fits your travel style and budget on Busbud.

    4. Which bus companies travel from Fort Pierce to Panama City?

      When taking the bus from Fort Pierce to Panama City, you can travel comfortably and safely with Greyhound, FlixBus.

    5. What are the departure and arrival stations when taking the bus from Fort Pierce to Panama City?

      Buses travelling between Fort Pierce and Panama City leave from Fort Pierce Bus Stop - Loves Gas Station or Port St Lucie Bus Stop and arrive at Panama City Greyhound Bus Station.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    31/10
    No data
    01/11
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    Today
    US$109
    03/11
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    busbud logoThe cheapest trip from Fort Pierce to Panama City, US was searched and found on 02 Nov 2025 with a price of US$109

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Pierce to Panama City, US as early as possible.

    About Bus Travel

    Bus Travel Tips

    If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Fort Pierce to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Fort Pierce to Panama City, get comfy and count the stars.

    Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Fort Pierce to Panama City that are otherwise impossible to come by with a plane.

    Tune out to the fine sounds of your best music playlist on your bus trip from Fort Pierce to Panama City while indulging in miles on end of beautiful scenic views.

    Did you know?

    9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

    Will you be returning to Fort Pierce by bus?

    Bus from Panama City, US to Fort Pierce

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