Find coaches from Greenville, SC to Lexington, KY

Previously seen journeys

Next departures from Greenville to Lexington on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
    		1116 Woodruff Rd
    		WJW Investments Bus StopNo tags
    Greyhound + FlixBus
      		1116 Woodruff Rd
      		WJW Investments Bus StopNo tags
      Greyhound + FlixBus
        		1116 Woodruff Rd
        		WJW Investments Bus StopNo tags
        FlixBus + Greyhound
          		1116 Woodruff Rd
          		WJW Investments Bus StopNo tags
          Greyhound
            		1116 Woodruff Rd
            		WJW Investments Bus StopNo tags

            Accepted payments

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            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Get from Greenville to Lexington

            This route is served by bus only

            The journey takes about 11 hours, and with fares starting at just US$53, it presents an excellent value for a comfortable ride.

            1bus per day
            11hAverage duration
            410 kmDistance
            10kgCO₂ emissions

            Bus Greenville, SC to Lexington, KY: Trip Overview

            Average ticket priceUS$128
            Average bus trip duration11h
            Number of daily buses1
            Earliest bus departure13:45
            Distance410 km
            Latest bus departure22:00

            Greenville to Lexington Bus

            Busbud helps you find a bus from Greenville to Lexington. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Lexington.

            From cheap bus tickets to more luxurious buses travelling from Greenville to Lexington, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Greenville, SC - Lexington, KY

            1. How much does a bus ticket from Greenville to Lexington cost?

              The bus ticket price from Greenville to Lexington starts at US$53. The best way to find cheap bus tickets from Greenville to Lexington is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Greenville to Lexington?

              The average travel time between Greenville and Lexington is around 11h, although the fastest bus will take about 11h. This is the time it takes to travel the 399 km that separates the two cities.

            3. How many daily bus connections are there between Greenville and Lexington?

              The number of buses from Greenville to Lexington can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Lexington by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Greenville to Lexington?

              When taking the bus from Greenville to Lexington, you can travel comfortably and safely with Greyhound.

            5. What are the departure and arrival stations when taking the bus from Greenville to Lexington?

              Buses travelling between Greenville and Lexington leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at WJW Investments Bus Stop, Bus Stop Lexington.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            US$115
            01/11
            US$45
            Today
            US$63
            03/11
            US$51
            04/11
            No data
            05/11
            No data
            06/11
            No data
            07/11
            No data
            busbud logoThe cheapest trip from Greenville, SC to Lexington, KY was searched and found on 01 Nov 2025 with a price of US$45

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Lexington, KY as early as possible.

            You can expect to pay from US$45 to US$115 for a bus ticket from Greenville, SC to Lexington, KY based on the last 2 days. You can expect to find the cheapest price for the trip at US$51, which is on 2025-11-03.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Lexington!

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Lexington.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Greenville to Lexington that are otherwise impossible to come by with a plane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Lexington while indulging in miles on end of beautiful scenic views.

            Did you know?

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Will you be returning to Greenville, SC by bus?

            Bus from Lexington, KY to Greenville, SC

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            Popular Buses Connecting Lexington

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