Based on 122 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the departure location and the cleanliness but often complained about the Wi-Fi. Pluss Chile ticket prices on this trip start at R 162
Pluss Chile La Serena Santiago de Chile recent customer reviews
The bus was very clean and comfortable. Just one problem - no paper in the toilet. Our driver was excellent. The gentleman who took tickets and luggage was also very nice. I felt safe and relaxed though out the 7-hour journey.
According to 12 reviews, Cikbus Elité received a 3.6-star rating for this journey. Travellers were especially satisfied with the staff and the seats, but some complained about the timeliness. Cikbus Elité ticket prices on this trip start at R 233
Based on 15567 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. FlixBus ticket prices on this trip start at R 224
Based on 25 reviews, the company was rated 3.2 stars on Busbud. Travellers were especially satisfied with the ticket access and the cleanliness but often complained about the Wi-Fi. Pullman San Andres ticket prices on this trip start at R 297
Based on 66 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the staff and the departure location but often complained about the Wi-Fi. Buses Romani ticket prices on this trip start at R 194
Buses Romani La Serena Santiago de Chile recent customer reviews
Based on 72 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Buses Andimar ticket prices on this trip start at R 245
Andimar La Serena Santiago de Chile recent customer reviews
Based on 75 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the departure location and the timeliness but often complained about the Wi-Fi. Buses Paravias ticket prices on this trip start at R 241
Paravias La Serena Santiago de Chile recent customer reviews
I had selected an upstairs aisle seat and ended up in a cramped downstairs window seat. Uncomfortable and no place to put personal belongings.
Based on 13 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the timeliness and the temperature but often complained about the value for money. Serena Mar ticket prices on this trip start at R 278
Serena Mar La Serena Santiago de Chile recent customer reviews
A good way to travel this route is with Turisnorte buses. The company offers 1 daily departures, with ticket prices starting at R 364 and the shortest trip taking about 7 hours 15 minutes. Turisnorte gets you where you want to go for a fair price.
Frequently asked questions about travelling from La Serena, CL to Santiago de Chile by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from La Serena to Santiago de Chile?
The cheapest bus tickets from La Serena to Santiago de Chile start at R 162. The average price for this route is around R 343. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from La Serena to Santiago de Chile?
The average bus journey time from La Serena to Santiago de Chile is 6h 30m, covering a distance of 398 km. The fastest bus gets you there in 3h 45m and is operated by Buses Romani.
Which bus companies service the La Serena to Santiago de Chile route?
What is the earliest and latest departure time for the bus from La Serena to Santiago de Chile?
The earliest bus departs from La Serena to Santiago de Chile at 00:00. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from La Serena to Santiago de Chile?
A bus trip from La Serena to Santiago de Chile produces an estimated 9.9359 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from La Serena to Santiago de Chile?
According to Busbud customers, the highest-rated bus company on this route is Pluss Chile, with an average rating of 3.9 out of 5 stars based on 120 reviews.
Which bus company has the best Wi-Fi from La Serena to Santiago de Chile?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from La Serena to Santiago de Chile?
According to Busbud traveller reviews, the most punctual bus company on this route is Serena Mar, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from La Serena to Santiago de Chile?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
06/09
R 336
07/09
R 217
Today
R 217
09/09
R 190
10/09
R 190
11/09
R 190
12/09
R 190
13/09
R 190
The cheapest trip from La Serena, CL to Santiago de Chile was searched and found on 09 Sept 2026 with a price of R 190
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Santiago de Chile as early as possible.
You can expect to pay from R 190 to R 723 for a bus ticket from La Serena, CL to Santiago de Chile based on the last 2 days. You can expect to find the cheapest price for the trip at R 190, which is on 2026-09-09.
Usually Pullman San Andres, Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from La Serena, CL to Santiago de Chile was searched and found on 09 Sept 2026 with a price of R 190
