Find coaches from Louisville to Knoxville, TN

Previously seen journeys

Next departures from Louisville to Knoxville on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Louisville, KY
    		Knoxville Bus StationNo tags
    Greyhound
      		Louisville, KY
      		Knoxville Bus StationNo tags
      Greyhound
        		Louisville, KY
        		Knoxville Bus StationNo tags
        Greyhound
          		Louisville, KY
          		Knoxville Bus StationNo tags
          Greyhound
            		Louisville, KY
            		Knoxville Bus StationNo tags

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            Get from Louisville to Knoxville

            This route is served by bus only

            The journey takes about 14 hours 5 minutes, and with fares starting at just US$50, it presents an excellent value for a comfortable ride.

            2bus per day
            14h 5mAverage duration
            302 kmDistance
            8kgCO₂ emissions

            Bus Louisville to Knoxville, TN: Trip Overview

            Average ticket priceUS$97
            Average bus trip duration14h 5m
            Number of daily buses2
            Earliest bus departure02:50
            Distance301 km
            Latest bus departure22:55

            Louisville to Knoxville Bus

            Busbud helps you find a bus from Louisville to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

            We make sure you can find a bus service from Louisville to Knoxville from the most reliable bus companies operating this trip.

            Discover how much the bus trip from Louisville to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Louisville - Knoxville, TN

            1. How much does a bus ticket from Louisville to Knoxville cost?

              The bus ticket price from Louisville to Knoxville starts at US$50. The best way to find cheap bus tickets from Louisville to Knoxville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Louisville to Knoxville?

              The average travel time between Louisville and Knoxville is around 14h 5m, although the fastest bus will take about 8h 20m. This is the time it takes to travel the 304 km that separates the two cities.

            3. How many daily bus connections are there between Louisville and Knoxville?

              The number of buses from Louisville to Knoxville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Louisville to Knoxville by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Louisville to Knoxville?

              When taking the bus from Louisville to Knoxville, you can travel comfortably and safely with Greyhound.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            No data
            01/11
            US$43
            Today
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            03/11
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            04/11
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            07/11
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            busbud logoThe cheapest trip from Louisville to Knoxville, TN was searched and found on 01 Nov 2025 with a price of US$43

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Knoxville, TN as early as possible.

            About Bus Travel

            Bus Travel Tips

            Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Knoxville!

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Louisville to Knoxville, get comfy and count the stars.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Louisville to Knoxville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Louisville to Knoxville.

            Did you know?

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            Will you be returning to Louisville by bus?

            Bus from Knoxville, TN to Louisville

            Why choose Busbud?

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