Find coaches from Portland, OR to Greenville, SC

Previously seen journeys

Next departures from Portland to Greenville on 17 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Portland Union Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Portland Union Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Portland Union Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Bus
Portland Union Station
1116 Woodruff RdNo tags
GreyhoundBus
Portland Curbside Bus Stop
1116 Woodruff RdNo tags

Compare 2 ways to travel from Portland to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 3 days, 2 hours 5 minutes and with fares starting at just R 5 398, it presents an excellent value for a comfortable ride.

2bus per day
3d 2hAverage duration
3587 kmDistance
90kgCO₂ emissions
Bus
Average priceR 5 398 - R 5 555Average duration3d 2h
90kg CO₂e
Train
Average priceR 11 371 - R 11 371Average duration3d 9h
325kg CO₂e

Frequently asked questions about travelling from Portland, OR to Greenville, SC by bus

  1. How much does a bus ticket from Portland to Greenville cost?

    The bus ticket price from Portland to Greenville starts at R 5 398. The best way to find cheap bus tickets from Portland to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Portland to Greenville?

    The average travel time between Portland and Greenville is around 3d 2h, although the fastest bus will take about 3d 2h. This is the time it takes to travel the 3583 km that separates the two cities.

  3. How many daily bus connections are there between Portland and Greenville?

    The number of buses from Portland to Greenville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Portland to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Portland to Greenville?

    When taking the bus from Portland to Greenville, you can travel comfortably and safely with Greyhound, FlixBus, Amtrak.

  5. What are the departure and arrival stations when taking the bus from Portland to Greenville?

    Buses travelling between Portland and Greenville leave from Portland Union Station or Portland Airport and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
14/11
R 9 354
15/11
No data
Today
No data
17/11
No data
18/11
No data
19/11
No data
20/11
No data
21/11
R 5 272
busbud logoThe cheapest trip from Portland, OR to Greenville, SC was searched and found on 21 Nov 2025 with a price of R 5 272

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to Greenville, SC as early as possible.

You can expect to pay from R 5 272 to R 9 354 for a bus ticket from Portland, OR to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 5 272, which is on 2025-11-21.

What's the cheapest way to go from Portland, OR to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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