Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags |
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Compare 2 ways to travel from Indianapolis to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 16 hours 15 minutes and with fares starting at just US$70, it presents an excellent value for a comfortable ride.
Train Indianapolis to Greenville, SC: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5561 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$156
Indianapolis to Greenville Train
With Busbud, comparing and booking tickets for a train from Indianapolis to Greenville is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Indianapolis to Greenville from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Greenville from Indianapolis, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions on the trip Indianapolis - Greenville, SC
How much does a cheap train ticket from Indianapolis to Greenville cost?
The average train ticket price from Indianapolis to Greenville is US$223. The best way to find cheap train tickets from Indianapolis to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Indianapolis to Greenville?
A train trip between Indianapolis and Greenville is around 1d 5h, although the fastest train will take about 1d 5h. This is the time it takes to travel the 641 km that separates the two cities.
How many daily train are there between Indianapolis and Greenville?
The number of trains from Indianapolis to Greenville can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Indianapolis to Greenville by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Indianapolis to Greenville?
When taking the train from Indianapolis to Greenville, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Greenville, SC was searched and found on 02 Nov 2025 with a price of US$133To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to Greenville, SC as early as possible.
You can expect to pay from US$133 to US$843 for a train ticket from Indianapolis to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$133, which is on 2025-11-02.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Indianapolis to Greenville is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Indianapolis and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Indianapolis to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Japanese trains are always on time. It is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologise to each passenger.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers travelled aboard the Shinkansen at a speed of 210 km / h.
Top Travelled Train Routes
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