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Find the cheapest bus tickets from Guayaquil to Santiago

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Guayaquil to Santiago Buses

With Busbud, comparing and booking tickets for a bus from Guayaquil to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Guayaquil to Santiago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Guayaquil, we help you find what you're looking for based on how much of a budget you have.

Stations & Stops

Need a bus leaving from Guayaquil? Your starting point is at Terminal Terrestre, BOL-GUAYAQUIL, Guayaquil, GUAYAQUIL or Terminal Aéreo Internacional.

If you're onboard a bus traveling to Santiago, you can get hop off at Terminal Sur, Terrapuerto Los Heroes, San Borja, Pajaritos, Omnium, Terminal ETM, Cruce Colon, Antonio Bellet, Arturo Alessandri or Bellavista.

Guayaquil to Santiago Route Map

Guayaquil to Santiago Route Map

Frequently asked questions for your trip Guayaquil - Santiago

What are the departure and arrival stations when taking the bus from Guayaquil to Santiago?

Buses traveling between Guayaquil and Santiago leave from Terminal Terrestre or BOL-GUAYAQUIL and arrive at Terminal Sur, Terrapuerto Los Heroes, San Borja.

What are the best sights and things to do in Santiago?

Once in Santiago, you can start exploring the city and discover its surroundings. The top sights and things to do are Cajon del Maipo, Teatro Municipal de Santiago, Museo Chileno de Arte Precolombino, Parque Forestal, Cerro San Cristóbal.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Guayaquil to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Guayaquil to Santiago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Guayaquil to Santiago.

Make a music playlist for your bus ride from Guayaquil to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Guayaquil by bus?

If you are looking for the return bus journey, check out buses from Santiago to Guayaquil.

Popular Buses Connecting Guayaquil

Popular Buses Connecting Santiago

Popular routes in this country

Why choose Busbud?

The Best Way To Book Bus Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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