Santiago to Guayaquil Buses
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Discover how much the bus trip from Santiago to Guayaquil will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Stations & Stops
Need a bus leaving from Santiago? Your starting point is at Terminal Sur, Terrapuerto Los Heroes, San Borja, Pajaritos, Omnium, Terminal ETM, Cruce Colon, Antonio Bellet, Arturo Alessandri or Bellavista.
Santiago to Guayaquil Route Map
Frequently asked questions for your trip Santiago - Guayaquil
What are the departure and arrival stations when taking the bus from Santiago to Guayaquil?
Buses traveling between Santiago and Guayaquil leave from Terminal Sur or Terrapuerto Los Heroes and arrive at Terminal Terrestre, BOL-GUAYAQUIL, Guayaquil.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Santiago to Guayaquil.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santiago to Guayaquil, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santiago to Guayaquil will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santiago to Guayaquil.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Will you be returning to Santiago by bus?
If you are looking for the return bus journey, check out buses from Guayaquil to Santiago.
Popular Buses Connecting Santiago
Buses Leaving from Santiago
Buses Going to Santiago
Popular Buses Connecting Guayaquil
Buses Leaving from Guayaquil
Buses Going to Guayaquil
Popular routes in this country
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