Train from Harrisburg to Greenville, SC: Tickets & Timetables

Previously seen journeys

Next departures from Harrisburg to Greenville on 3 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags

Compare 2 ways to travel from Harrisburg to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just £127, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage duration
480 milesDistance
70kgCO₂ emissions
Average price£91 - £285Average duration22h 45m
19kg CO₂e
Average price£127 - £520Average duration16h 19m
70kg CO₂e

Frequently asked questions about travelling from Harrisburg to Greenville, SC by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a train ticket cost from Harrisburg to Greenville?

    The cheapest train tickets from Harrisburg to Greenville start from £127. The average price for this train route is around £200. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the train journey from Harrisburg to Greenville?

    The average train journey time from Harrisburg to Greenville is 16h 19m, covering a distance of 480 miles. The fastest train gets you there in 16h 19m and is operated by Amtrak.

  3. Which train operators serve the Harrisburg to Greenville route?

    Several major train operators run on this route with 1 trains available per day.

  4. What are the earliest and latest departure times for the train from Harrisburg to Greenville?

    The earliest train from Harrisburg to Greenville departs at 11:20. And the latest train departs at 13:05.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/12
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02/12
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Today
£193
04/12
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05/12
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06/12
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busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on 3 Dec 2025 with a price of £193

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Greenville, SC as early as possible.

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