Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | Cheapest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | Fastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Yesterday at 10:03 CEST.
Compare 2 ways to travel from Brussels to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes and with fares starting at just THB 873, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia - B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Holešovice
Praha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia - E
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - F
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Train Companies
Based on 12 reviews, the company was rated 4 stars on Busbud. Travellers were especially satisfied with the ticket access and the departure location but often complained with the Wi-Fi. Deutsche Bahn ticket prices on this trip start at THB 8,111
Frequently asked questions about travelling from Brussels to Prague by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start from THB 3,673. The average price for this train route is around THB 5,000. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Brussels to Prague?
The average train journey time from Brussels to Prague is 16h 48m, covering a distance of 720 km. The fastest train gets you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators serve the Brussels to Prague route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Brussels to Prague?
The earliest train from Brussels to Prague departs at 18:06. And the latest train departs at 19:22.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on 23 Sept 2026 with a price of THB 4,411To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague as early as possible.
You can expect to pay from THB 4,411 to THB 44,100 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at THB 4,411, which is on 2026-09-23.
