Next train departures

Next departures from Syracuse to Buffalo on 17 April
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	22:05	Amtrak Station	2h 24m	00:29	Depew Station	CheapestFastest
	Train	22:05	Amtrak Station	2h 24m	00:29	Depew Station	No tags

Next departures from Syracuse to Buffalo on 18 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 19 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	16:02	Amtrak Station	2h 32m	18:34	Depew Station	Cheapest
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	Fastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 20 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 21 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	16:02	Amtrak Station	2h 32m	18:34	Depew Station	Cheapest
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	Fastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 24 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Last refresh of the prices: Yesterday at 18:08 EDT.

Compare 2 ways to travel from Syracuse to Buffalo

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Buffalo. The journey takes about 2 hours 32 minutes and with fares starting at just MX$516, it presents an excellent value for a comfortable ride.

7train per day

2h 32mAverage duration

215 kmDistance

19kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceMX$497 - MX$1,364	Average duration3h 5m	CO₂ emissions 5kg CO₂e
Train	Average priceMX$516 - MX$1,412	Average duration2h 32m	CO₂ emissions 19kg CO₂e

Where are the popular train stations and stops in Syracuse, US and Buffalo, NY?

Syracuse, US

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/04

MX$478

16/04

MX$478

Today

MX$478

18/04

MX$478

19/04

MX$478

20/04

MX$478

21/04

MX$478

22/04

No data

The cheapest trip from Syracuse, US to Buffalo, NY was searched and found on 15 Apr 2026 with a price of MX$478

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Buffalo, NY as early as possible.

You can expect to pay from MX$478 to MX$9,545 for a train ticket from Syracuse, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at MX$478, which is on 2026-04-18.