Next train departures

Next departures from Syracuse to Buffalo on 17 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	18:59	Amtrak Station	2h 22m	21:21	Depew Station	CheapestFastest
Train	18:59	Amtrak Station	2h 43m	21:42	Exchange Street Station	No tags
Train	18:59	Amtrak Station	2h 43m	21:42	Exchange Street Station	No tags
Train	18:59	Amtrak Station	2h 22m	21:21	Depew Station	No tags
Train	22:05	Amtrak Station	2h 24m	00:29	Depew Station	No tags

Next departures from Syracuse to Buffalo on 18 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 19 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	16:02	Amtrak Station	2h 32m	18:34	Depew Station	Cheapest
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	Fastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 20 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 21 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	16:02	Amtrak Station	2h 32m	18:34	Depew Station	Cheapest
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	Fastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Next departures from Syracuse to Buffalo on 24 April
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:57	Amtrak Station	2h 22m	15:19	Depew Station	CheapestFastest
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	12:57	Amtrak Station	2h 35m	15:32	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags
Train	16:02	Amtrak Station	2h 53m	18:55	Exchange Street Station	No tags

Last refresh of the prices: Yesterday at 18:08 EDT.

Compare 2 ways to travel from Syracuse to Buffalo

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Buffalo. The journey takes about 2 hours 32 minutes and with fares starting at just TRY 1,341, it presents an excellent value for a comfortable ride.

7train per day

2h 32mAverage duration

215 kmDistance

19kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceTRY 1,292 - TRY 3,547	Average duration3h 5m	CO₂ emissions 5kg CO₂e
Train	Average priceTRY 1,341 - TRY 3,672	Average duration2h 32m	CO₂ emissions 19kg CO₂e

Where are the popular train stations and stops in Syracuse, US and Buffalo, NY?

Syracuse, US

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/04

TRY 1,242

16/04

TRY 1,242

Today

TRY 1,242

18/04

TRY 1,242

19/04

TRY 1,242

20/04

TRY 1,242

21/04

TRY 1,242

22/04

No data

The cheapest trip from Syracuse, US to Buffalo, NY was searched and found on 15 Apr 2026 with a price of TRY 1,242

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Buffalo, NY as early as possible.

You can expect to pay from TRY 1,242 to TRY 24,822 for a train ticket from Syracuse, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at TRY 1,242, which is on 2026-04-18.