Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Depew Station | Amtrak Station | CheapestFastest | ||||
| Train | Depew Station | Amtrak Station | No tags | ||||
| Train | Depew Station | Amtrak Station | No tags | ||||
| Train | Exchange Street Station | Amtrak Station | No tags | ||||
| Train | Exchange Street Station | Amtrak Station | No tags |
Last refresh of the prices: Yesterday at 15:22 EST.
Compare 2 ways to travel from Buffalo to Charlotte
Among the sustainable travel choices, the train stands out as a good way to reach Charlotte. The journey takes about 21 hours 45 minutes and with fares starting at just £143, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5639 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £143
Frequently asked questions about travelling from Buffalo, NY to Charlotte, NC by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Buffalo to Charlotte?
The cheapest train tickets from Buffalo to Charlotte start from £143. The average price for this train route is around £247. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Buffalo to Charlotte?
The average train journey time from Buffalo to Charlotte is 21h 45m, covering a distance of 541 miles. The fastest train gets you there in 21h 45m and is operated by Amtrak.
Which train operators serve the Buffalo to Charlotte route?
Several major train operators run on this route with 2 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to Charlotte?
The earliest train from Buffalo to Charlotte departs at 04:28. And the latest train departs at 04:45.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Charlotte, NC was searched and found on 10 Dec 2025 with a price of £189To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Charlotte, NC as early as possible.
You can expect to pay from £189 to £630 for a train ticket from Buffalo, NY to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at £221, which is on 2025-12-15.
