Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Durham Station | Chicago (Union Station), IL | CheapestFastest | ||||
| Train | Durham Station | Chicago (Union Station), IL | No tags | ||||
| Train | Durham Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Yesterday at 19:18 EDT.
Compare 2 ways to travel from Durham to Chicago
Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 50 minutes and with fares starting at just £72, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5815 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at £147
Frequently asked questions about travelling from Durham, NC, US to Chicago by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Durham to Chicago?
The cheapest train tickets from Durham to Chicago start from £147. The average price for this train route is around £284. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Durham to Chicago?
The average train journey time from Durham to Chicago is 1d 13h, covering a distance of 619 miles. The fastest train gets you there in 1d 13h and is operated by Amtrak.
Which train operators serve the Durham to Chicago route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Durham to Chicago?
The earliest train from Durham to Chicago departs at 19:58. And the latest train departs at 20:03.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Chicago was searched and found on 6 Jun 2026 with a price of £167To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to Chicago as early as possible.
You can expect to pay from £167 to £1,065 for a train ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £167, which is on 2026-06-06.
