Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
DB Fernverkehr + Deutsche Bahn + DB Regio Bayern + alex - Die Länderbahn | Train | Mannheim Train station | Hlavní nádraží | Cheapest | ||||
 | Train | Mannheim Train station | Hlavní nádraží | Fastest | ||||
DB Regio Mitte + DB Fernverkehr + Ceske Drahy | Train | Mannheim ARENA/Maimarkt | Hlavní nádraží | No tags | ||||
DB Regio Mitte + DB Fernverkehr + DB Regio Südost + Ceske Drahy | Train | Mannheim ARENA/Maimarkt | Hlavní nádraží | No tags | ||||
DB Regio Mitte + DB Fernverkehr | Train | Mannheim ARENA/Maimarkt | Hlavní nádraží | No tags |
Last refresh of the prices: Today at 21:01 CEST.
Compare 2 ways to travel from Mannheim to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 7 hours 45 minutes and with fares starting at just COP 133,363, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Mannheim and Prague?
Mannheim
- AWilly-Brandt-Platz 17, 68161 Mannheim, Germany
- BHeinrich-von-Stephan-Straße 4-6, 68161 Mannheim, Germany
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- BPrague Main Railway Station, 120 00 Praha-Praha 2, Czechia
- CAviatická, 161 08, Praha 6, Czechia
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- EChlumecká, 198 00 Praha 20, Czech Republic
- FPraha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia
Train Companies
Based on 1 reviews, the company was rated 5 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Deutsche Bahn EuroCity ticket prices on this trip start at COP 146,008
Frequently asked questions about travelling from Mannheim to Prague by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Mannheim to Prague?
The cheapest train tickets from Mannheim to Prague start from COP 315,013. The average price for this train route is around COP 315,013. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Mannheim to Prague?
The average train journey time from Mannheim to Prague is 11h 56m, covering a distance of 269 miles. The fastest train gets you there in 9h 43m and is operated by Deutsche Bahn EuroCity.
Which train operators serve the Mannheim to Prague route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Mannheim to Prague?
The earliest train from Mannheim to Prague departs at 21:29. And the latest train departs at 21:29.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on 9 May 2026 with a price of COP 258,284To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Mannheim to Prague as early as possible.
You can expect to pay from COP 258,284 to COP 1,237,551 for a train ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at COP 554,463, which is on 2026-05-11.
