Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Mannheim Train station | Hlavní nádraží | Cheapest | ||||
| Train | Mannheim Train station | Hlavní nádraží | Fastest | ||||
DB Regio Mitte + DB Fernverkehr + DB Regio Südost + Ceske Drahy | Train | Mannheim ARENA/Maimarkt | Hlavní nádraží | No tags | ||||
DB Regio Mitte + Deutsche Bahn + DB Regio Bayern + alex - Die Länderbahn | Train | Mannheim ARENA/Maimarkt | Hlavní nádraží | No tags | ||||
| Train | Mannheim Train station | Hlavní nádraží | No tags |
Last refresh of the prices: Last Tuesday at 3:55 PM CEST.
Compare 2 ways to go from Mannheim to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 7 hours 45 minutes, and with fares starting at just $50, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Mannheim and Prague?
Mannheim
- AWilly-Brandt-Platz 17, 68161 Mannheim, Germany
- BHeinrich-von-Stephan-Straße 4-6, 68161 Mannheim, Germany
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- BPrague Main Railway Station, 120 00 Praha-Praha 2, Czechia
- CAviatická, 161 08, Praha 6, Czechia
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- EChlumecká, 198 00 Praha 20, Czech Republic
- FPraha-Holešovice, Partyzánská 1546/26, 170 00 Praha 7-Holešovice, Czechia
Train companies
Frequently asked questions about travelling from Mannheim to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Mannheim to Prague?
The cheapest train tickets from Mannheim to Prague start at $60. The average price for this train route is around $198. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Mannheim to Prague?
The average train trip from Mannheim to Prague takes 9h 7m and covers 433 km. The quickest train gets you there in 7h 56m and is operated by Deutsche Bahn.
Which train operators serve the Mannheim to Prague route?
Several major train operators serve this route, with 28 trains available per day, including services from Deutsche Bahn, Deutsche Bahn EuroCity.
What are the earliest and latest departure times for the train from Mannheim to Prague?
The earliest train from Mannheim to Prague departs at 6:03am. The latest train departs at 11:51pm.
What is the best train operator from Mannheim to Prague?
According to Busbud customers, the highest-rated train operator on this route is Deutsche Bahn EuroCity, with an average rating of 5.0 out of 5 stars based on 1 reviews.
Which train operator has the best Wi-Fi from Mannheim to Prague?
Based on reviews on Busbud, the train operator Deutsche Bahn EuroCity has the best Wi-Fi rating with a score of 5.0.
Which train operator has the best on-time performance from Mannheim to Prague?
According to Busbud traveller reviews, the most punctual train operator on this route is Deutsche Bahn EuroCity, with a punctuality rating of 5.0 out of 5 stars.
Which train operator has the cleanest trains from Mannheim to Prague?
According to Busbud traveller reviews, the train operator with the cleanest trains on this route is Deutsche Bahn EuroCity, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on May 15, 2026 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Mannheim to Prague, as early as possible.
You can expect to pay from $68 to $400 for a train ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2026-05-15.
