Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Viale Toselli (Penny Market) | Aéroport LYS | No tags | ||||
| Bus | Siena Train Station | Perrache | No tags | ||||
| Bus | Siena Train Station | Aéroport LYS | No tags | ||||
| Bus | Viale Toselli (Penny Market) | Perrache | No tags | ||||
| Bus | Siena Train Station | Perrache | No tags |
Get from Siena to Lyon
The journey takes about 15 hours 35 minutes, and with fares starting at just €55, it presents an excellent value for a comfortable ride.
Where are the popular stops in Siena and Lyon?
Stops in Siena
- APiazza Antonio Gramsci, 53100 Siena SI, Italy
- B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Based on 12232 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at €55
Frequently asked questions about travelling by bus from Siena to Lyon
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Siena to Lyon?
The cheapest coach tickets from Siena to Lyon start from €55. The average price for this route is around €65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Siena to Lyon?
The average bus journey time from Siena to Lyon is 15h 35m, covering a distance of 580 km. The fastest bus can take you there in 12h and is operated by FlixBus.
Which bus companies service the Siena to Lyon route?
Several major bus companies operate on this route with 12 buses available per day.
What is the earliest and latest departure time for the bus from Siena to Lyon?
The earliest bus departs from Siena to Lyon at 00:45. And the latest bus departs at 20:25.
What are the CO₂ emissions for the bus trip from Siena to Lyon?
A bus journey from Siena to Lyon produces an estimated 14 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Siena to Lyon was searched and found on 20 Feb 2026 with a price of €52To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Lyon as early as possible.
