Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags |
Compare 2 ways to travel from Indianapolis to Buffalo
Among the sustainable travel choices, the Bus stands out as a good way to reach Buffalo. The journey takes about 16 hours 45 minutes and with fares starting at just R 1 577, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Indianapolis and Buffalo, NY?
Train Companies
Based on 5754 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained about the Wi-Fi. Amtrak ticket prices on this trip start at R 2 365
Frequently asked questions about travelling from Indianapolis to Buffalo, NY by train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the train ticket from Indianapolis to Buffalo?
The cheapest train tickets from Indianapolis to Buffalo start from R 2 365. The average price for this train route is around R 2 690. Busbud recommends booking your tickets in advance for a better chance to secure the lowest possible price.
How long is the train journey from Indianapolis to Buffalo?
The average train journey time from Indianapolis to Buffalo is 1d 2h, covering a distance of 713 km. The quickest train can get you there in 1d 2h and is operated by Amtrak.
Which train operators serve the Indianapolis to Buffalo route?
Several major train operators run on this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Indianapolis to Buffalo?
The earliest train from Indianapolis to Buffalo departs at 06:00. And the latest train departs at 06:25.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Buffalo, NY was searched and found on 31 Jan 2026 with a price of R 2 266To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to Buffalo, NY as early as possible.
