How much is the train ticket from Waterloo to St. Louis?

The cheapest train tickets from Waterloo to St. Louis start from $70. The average price for this train route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Waterloo to St. Louis?

The average train ride duration from Waterloo to St. Louis is 16h 47m, covering a distance of 335 miles (541 km). The quickest train can get you there in 12h 16m and is operated by Amtrak .

Which train operators service the Waterloo to St. Louis route?

Several major train operators operate on this route with 4 trains available per day.

What is the earliest and latest departure time for the train from Waterloo to St. Louis?

The earliest train departs from Waterloo to St. Louis at 6:36am. And the latest train departs at 7:51am.

Train Waterloo to St. Louis from $78 | Refundable Tickets

Next train departures

Next departures for Waterloo to St. Louis on December 18
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:51am	Waterloo Station	12h 16m	7:07pm	Gateway Station	CheapestFastest
Train	7:51am	Waterloo Station	12h 16m	7:07pm	Gateway Station	No tags
Train	7:51am	Waterloo Station	12h 16m	7:07pm	Gateway Station	No tags
Train	7:51am	Waterloo Station	17h 18m	12:09am	Gateway Station	No tags
Train	7:51am	Waterloo Station	17h 18m	12:09am	Gateway Station	No tags

Last refresh of the prices: Yesterday at 8:12 PM EST.

Get from Waterloo to St. Louis

This route is served by train only

The journey takes about 16 hours 47 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.

4train per day

16h 47mAverage Duration

335 milesDistance

49kgCO₂ emissions

Where are the popular train stations and stops in Waterloo, IN, US and St. Louis?

Waterloo, IN, US

A
Waterloo Station
485 W Van Vleek St, Waterloo, IN 46793, USA
Visit page

St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Train Companies

Amtrak

4/55,652 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5652 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $70

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Waterloo, IN, US to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Waterloo to St. Louis?
The cheapest train tickets from Waterloo to St. Louis start from $70. The average price for this train route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Waterloo to St. Louis?
The average train ride duration from Waterloo to St. Louis is 16h 47m, covering a distance of 335 miles (541 km). The quickest train can get you there in 12h 16m and is operated by Amtrak.
Which train operators service the Waterloo to St. Louis route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the train from Waterloo to St. Louis?
The earliest train departs from Waterloo to St. Louis at 6:36am. And the latest train departs at 7:51am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/16

No data

12/17

$55

Today

$122

12/19

$127

12/20

No data

12/21

No data

12/22

$102

12/23

No data

The cheapest trip from Waterloo, IN, US to St. Louis was searched and found on Dec 17, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Waterloo, IN, US to St. Louis, as early as possible.

You can expect to pay from $55 to $699 for a train ticket from Waterloo, IN, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-12-22.