How much is the train ticket from Indianapolis to St. Louis?

The cheapest train tickets from Indianapolis to St. Louis start at $91. The average price for this train route is around $169. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

How long is the train ride from Indianapolis to St. Louis?

The average train trip from Indianapolis to St. Louis takes 17h 23m and covers 371 km. The quickest train gets you there in 14h 7m and is operated by Amtrak .

Which train operators serve the Indianapolis to St. Louis route?

Several major train operators serve this route, with 1 trains available per day.

What are the earliest and latest departure times for the train from Indianapolis to St. Louis?

The earliest train from Indianapolis to St. Louis departs at 6:00am. The latest train departs at 6:00am.

Train Indianapolis to St. Louis from $123 | Refundable Tickets

Next train departures

Next departures for Indianapolis to St. Louis on December 13
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	Cheapest
Train	6:00am	Greyhound Amtrak Station	14h 7m	7:07pm	Gateway Station	Fastest
Train	6:00am	Greyhound Amtrak Station	14h 7m	7:07pm	Gateway Station	No tags
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	No tags
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	No tags

Next departures for Indianapolis to St. Louis on December 15
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	Cheapest
Train	6:00am	Greyhound Amtrak Station	14h 7m	7:07pm	Gateway Station	Fastest
Train	6:00am	Greyhound Amtrak Station	14h 7m	7:07pm	Gateway Station	No tags
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	No tags
Train	6:00am	Greyhound Amtrak Station	17h 23m	10:23pm	Gateway Station	No tags

Last refresh of the prices: Today at 6:04 AM EST.

Compare 2 ways to go from Indianapolis to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 4 hours 20 minutes, and with fares starting at just $47, it presents an excellent value for a comfortable ride.

3bus per day

4h 20mAverage Duration

371 kmDistance

9kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$47 - $141	Average Duration4h 20m	CO₂ emissions 9kg CO₂e
Train	Average Price$91 - $781	Average Duration17h 23m	CO₂ emissions 34kg CO₂e

Where are the popular train stations and stops in Indianapolis and St. Louis?

Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Train companies

Amtrak

4/55,637 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5637 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $91

US train and bus companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about travelling from Indianapolis to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Indianapolis to St. Louis?
The cheapest train tickets from Indianapolis to St. Louis start at $91. The average price for this train route is around $169. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Indianapolis to St. Louis?
The average train trip from Indianapolis to St. Louis takes 17h 23m and covers 371 km. The quickest train gets you there in 14h 7m and is operated by Amtrak.
Which train operators serve the Indianapolis to St. Louis route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Indianapolis to St. Louis?
The earliest train from Indianapolis to St. Louis departs at 6:00am. The latest train departs at 6:00am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-09

No data

12-10

No data

Today

$162

12-12

No data

12-13

$177

12-14

No data

12-15

$162

12-16

No data

The cheapest trip from Indianapolis to St. Louis was searched and found on Dec 11, 2025 with a price of $162

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to St. Louis, as early as possible.

You can expect to pay from $162 to $660 for a train ticket from Indianapolis to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $162 which is on 2025-12-15.