Previously seen trips

Next departures for Antwerp to Prague on December 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Deutsche Bahn + Deutsche Bahn EuroCity + Deutsche Bahn ICE	Train	9:25pm	Antwerp Central Train Station	15h 58m	1:23pm	Hlavní nádraží	No tags
Deutsche Bahn + Deutsche Bahn ICE + Deutsche Bahn EuroCity	Train	9:25pm	Antwerp Central Train Station	15h 58m	1:23pm	Hlavní nádraží	No tags
Deutsche Bahn EuroCity + Deutsche Bahn	Train	9:25pm	Antwerp Central Train Station	17h 58m	3:23pm	Hlavní nádraží	No tags
Deutsche Bahn + Deutsche Bahn EuroCity + Deutsche Bahn ICE	Train	7:54am	Antwerp Central Train Station	13h 29m	9:23pm	Hlavní nádraží	No tags
Deutsche Bahn EuroCity + Deutsche Bahn + Deutsche Bahn ICE	Train	3:25pm	Antwerp Central Train Station	13h 58m	5:23am	Hlavní nádraží	No tags

Compare 2 ways to go from Antwerp to Prague

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 10 minutes, and with fares starting at just $77, it presents an excellent value for a comfortable ride.

26bus per day

19h 10mAverage Duration

718 kmDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$77 - $360	Average Duration19h 10m	CO₂ emissions 18kg CO₂e
Train	Average Price$167 - $740	Average Duration15h 17m	CO₂ emissions 17kg CO₂e

Where are the popular train stations and stops in Antwerp and Prague?

Antwerp

A
Antwerpen-Berchem
Binnensingel 189, 2600 Antwerpen, Belgium
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Prague

A
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
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B
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
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C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
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D
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia
E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
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F
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
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Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-20

No data

12-21

No data

Today

$439

12-23

No data

12-24

No data

12-25

No data

12-26

$236

12-27

No data

The cheapest trip from Antwerp to Prague was searched and found on Dec 26, 2025 with a price of $236

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Antwerp to Prague, as early as possible.

You can expect to pay from $236 to $1,363 for a train ticket from Antwerp to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $236 which is on 2025-12-26.