How much is the train ticket from Framingham to St. Louis?

The cheapest train tickets from Framingham to St. Louis start at $301. The average price for this train route is around $301. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

How long is the train ride from Framingham to St. Louis?

The average train trip from Framingham to St. Louis takes 1d 6h and covers 1637 km. The quickest train gets you there in 1d 6h and is operated by Amtrak .

Which train operators serve the Framingham to St. Louis route?

Several major train operators serve this route, with 2 trains available per day.

What are the earliest and latest departure times for the train from Framingham to St. Louis?

The earliest train from Framingham to St. Louis departs at 1:25pm. The latest train departs at 1:25pm.

Train Framingham to St. Louis from $198 | Refundable Tickets

Next train departures

Next departures for Framingham to St. Louis on December 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags

Next departures for Framingham to St. Louis on December 31
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	No tags

Next departures for Framingham to St. Louis on January 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	No tags

Next departures for Framingham to St. Louis on January 2
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags

Next departures for Framingham to St. Louis on January 3
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 6h	7:07pm	Gateway Station	No tags

Next departures for Framingham to St. Louis on January 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	Cheapest
Train	1:25pm	Framingham Intermodal	1d 7h	7:25pm	Gateway Station	Fastest
Train	1:25pm	Framingham Intermodal	1d 7h	7:25pm	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags
Train	1:25pm	Framingham Intermodal	1d 11h	12:09am	Gateway Station	No tags

Last refresh of the prices: Last Sunday at 8:15 AM EST.

Compare 2 ways to go from Framingham to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 1 day, 6 hours 42 minutes, and with fares starting at just $301, it presents an excellent value for a comfortable ride.

2train per day

1d 6hAverage Duration

1637 kmDistance

149kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$212 - $323	Average Duration1d 12h	CO₂ emissions 41kg CO₂e
Train	Average Price$301 - $343	Average Duration1d 6h	CO₂ emissions 149kg CO₂e

Train companies

Amtrak

4/55,688 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5688 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $301

US train and bus companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about travelling from Framingham to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Framingham to St. Louis?
The cheapest train tickets from Framingham to St. Louis start at $301. The average price for this train route is around $301. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Framingham to St. Louis?
The average train trip from Framingham to St. Louis takes 1d 6h and covers 1637 km. The quickest train gets you there in 1d 6h and is operated by Amtrak.
Which train operators serve the Framingham to St. Louis route?
Several major train operators serve this route, with 2 trains available per day.
What are the earliest and latest departure times for the train from Framingham to St. Louis?
The earliest train from Framingham to St. Louis departs at 1:25pm. The latest train departs at 1:25pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-28

No data

12-29

$466

Today

$466

12-31

$337

The cheapest trip from Framingham to St. Louis was searched and found on Dec 31, 2025 with a price of $337

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Framingham to St. Louis, as early as possible.

You can expect to pay from $337 to $3,515 for a train ticket from Framingham to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $337 which is on 2025-12-31.