Train from Chicago to San Diego, CA, US: Tickets & Timetables
Next train departures
Next departures from Chicago to San Diego on 27 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Chicago (Union Station), IL
Santa Fe Depot
Cheapest
Train
Chicago (Union Station), IL
Old Town San Diego
Fastest
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Next departures from Chicago to San Diego on 28 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Chicago (Union Station), IL
Santa Fe Depot
Cheapest
Train
Chicago (Union Station), IL
Old Town San Diego
Fastest
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Next departures from Chicago to San Diego on 29 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Chicago (Union Station), IL
Santa Fe Depot
Cheapest
Train
Chicago (Union Station), IL
Old Town San Diego
Fastest
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Next departures from Chicago to San Diego on 30 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Chicago (Union Station), IL
Santa Fe Depot
Cheapest
Train
Chicago (Union Station), IL
Old Town San Diego
Fastest
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Next departures from Chicago to San Diego on 1 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Chicago (Union Station), IL
Santa Fe Depot
Cheapest
Train
Chicago (Union Station), IL
Old Town San Diego
Fastest
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Train
Chicago (Union Station), IL
Santa Fe Depot
No tags
Last refresh of the prices: Yesterday at 20:18 CST.
Compare 2 ways to travel from Chicago to San Diego
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach San Diego. The journey takes about 2 days, 42 minutes and with fares starting at just £139, it presents an excellent value for a comfortable ride.
Based on 5751 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at £139
Frequently asked questions about travelling from Chicago to San Diego, CA, US by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Chicago to San Diego?
The cheapest train tickets from Chicago to San Diego start from £139. The average price for this train route is around £164. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Chicago to San Diego?
The average train journey time from Chicago to San Diego is 2d , covering a distance of 1728 miles. The fastest train gets you there in 2d and is operated by Amtrak.
Which train operators serve the Chicago to San Diego route?
Several major train operators run on this route with 3 trains available per day.
What are the earliest and latest departure times for the train from Chicago to San Diego?
The earliest train from Chicago to San Diego departs at 13:52. And the latest train departs at 14:25.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
25/01
£154
26/01
£183
Today
£183
28/01
£214
29/01
£183
30/01
£214
31/01
No data
01/02
£214
The cheapest trip from Chicago to San Diego, CA, US was searched and found on 25 Jan 2026 with a price of £154
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to San Diego, CA, US as early as possible.
You can expect to pay from £154 to £1,120 for a train ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £183, which is on 2026-01-29.
The cheapest trip from Chicago to San Diego, CA, US was searched and found on 25 Jan 2026 with a price of £154
