Find coaches from Chicago to San Diego, CA, US

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Today26 Jul
from US$275
Tomorrow27 Jul
from US$191
Mon28 Jul
from US$184
Tue29 Jul
Wed30 Jul
Thu31 Jul
Fri1 Aug
Sat2 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 27 July at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: 30 July at
    Destination city: San Diego
    Destination location: Downtown SD (Seaport)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 27 July at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: 29 July at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: 29 July at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: 29 July at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: 29 July at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Chicago to San Diego

Bus
Average priceUS$108 - US$729Average duration2d 8h
70kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$345 - US$345Average duration2d 17h
254kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to San Diego

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 8 hours 15 minutes and with fares starting at just US$108, it presents an excellent value for a comfortable ride.

22bus per day
2d 8hAverage duration
US$108Cheapest ticket
70kgCO₂ emissions

Bus Chicago to San Diego, CA, US: Trip Overview

Average ticket priceUS$179
Average bus trip duration2d 8h
Number of daily buses22
Earliest bus departure00:15
Distance1727 miles
Latest bus departure23:50

Chicago to San Diego Bus

Busbud helps you find a bus from Chicago to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Chicago to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Chicago to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Chicago - San Diego, CA, US

  1. What's the distance between Chicago and San Diego by coach?

    The distance between Chicago and San Diego by coach is approximately 1729 miles (2788 km).

  2. What is the best way to go from Chicago to San Diego without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/07
US$190
25/07
US$389
Today
US$226
27/07
US$216
28/07
US$191
29/07
US$134
30/07
US$176
31/07
US$196
busbud logoThe cheapest trip from Chicago to San Diego, CA, US was searched and found on 29 Jul 2025 with a price of US$134

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, CA, US as early as possible.

You can expect to pay from US$134 to US$435 for a bus ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$134, which is on 2025-07-29.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and San Diego!

Much more than a mere vehicle taking you from Chicago to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to San Diego that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Chicago to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Chicago to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Chicago to San Diego, CA, US

You can also go to San Diego, CA, US by train

Train from Chicago to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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Popular bus departures from Chicago

Popular bus departures to Chicago

Continue your journey from San Diego