Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Florence Station | Depew Station | No tags | ||||
| Train | Florence Station | Exchange Street Station | No tags | ||||
| Train | Florence Station | Depew Station | No tags | ||||
| Train | Florence Station | Depew Station | No tags | ||||
| Train | Florence Station | Exchange Street Station | No tags |
Compare 2 ways to travel from Florence to Buffalo
Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 1 hour and with fares starting at just £91, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5657 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £171
Frequently asked questions about travelling from Florence, SC, US to Buffalo, NY by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Florence to Buffalo?
The cheapest train tickets from Florence to Buffalo start from £171. The average price for this train route is around £224. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Florence to Buffalo?
The average train journey time from Florence to Buffalo is 22h 10m, covering a distance of 603 miles. The fastest train gets you there in 21h 49m and is operated by Amtrak.
Which train operators serve the Florence to Buffalo route?
Several major train operators run on this route with 2 trains available per day.
What are the earliest and latest departure times for the train from Florence to Buffalo?
The earliest train from Florence to Buffalo departs at 22:32. And the latest train departs at 23:32.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Buffalo, NY was searched and found on 18 Dec 2025 with a price of £171To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Buffalo, NY as early as possible.
You can expect to pay from £171 to £758 for a train ticket from Florence, SC, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at £185, which is on 2025-12-20.
