Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greenville Station | Greyhound Amtrak Station | No tags | ||||
| Train | Greenville Station | Greyhound Amtrak Station | No tags | ||||
| Train | Greenville Station | Greyhound Amtrak Station | No tags | ||||
| Train | Greenville Station | Greyhound Amtrak Station | No tags | ||||
| Train | Greenville Station | Greyhound Amtrak Station | No tags |
Compare 2 ways to travel from Greenville to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 17 hours 40 minutes and with fares starting at just £66, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5742 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £134
Frequently asked questions about travelling from Greenville, SC to Indianapolis by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Greenville to Indianapolis?
The cheapest train tickets from Greenville to Indianapolis start from £134. The average price for this train route is around £150. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Greenville to Indianapolis?
The average train journey time from Greenville to Indianapolis is 1d 2h, covering a distance of 396 miles. The fastest train gets you there in 1d 2h and is operated by Amtrak.
Which train operators serve the Greenville to Indianapolis route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Greenville to Indianapolis?
The earliest train from Greenville to Indianapolis departs at 02:23. And the latest train departs at 02:23.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Indianapolis was searched and found on 21 Jan 2026 with a price of £102To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Indianapolis as early as possible.
You can expect to pay from £102 to £688 for a train ticket from Greenville, SC to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at £102, which is on 2026-01-21.
