Train from Orlando to Florence, SC, US: Tickets & Timetables

Next train departures

Next departures from Orlando to Florence on 14 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Orlando Health / Amtrak Station
Florence StationCheapest
AmtrakTrain
Orlando Health / Amtrak Station
Florence StationFastest
AmtrakTrain
Orlando Health / Amtrak Station
Florence StationNo tags
AmtrakTrain
Orlando Health / Amtrak Station
Florence StationNo tags
AmtrakTrain
Orlando Health / Amtrak Station
Florence StationNo tags

Last refresh of the prices: Last Wednesday at 22:25 EST.

Compare 2 ways to travel from Orlando to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 9 hours 35 minutes and with fares starting at just £48, it presents an excellent value for a comfortable ride.

3bus per day
9h 35mAverage duration
401 milesDistance
16kgCO₂ emissions
Average price£48 - £169Average duration9h 35m
16kg CO₂e
Average price£49 - £523Average duration15h 59m
59kg CO₂e

Frequently asked questions about travelling from Orlando to Florence, SC, US by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much does a train ticket cost from Orlando to Florence?

    The cheapest train tickets from Orlando to Florence start from £49. The average price for this train route is around £74. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the train journey from Orlando to Florence?

    The average train journey time from Orlando to Florence is 15h 59m, covering a distance of 403 miles. The fastest train gets you there in 9h 46m and is operated by Amtrak.

  3. Which train operators serve the Orlando to Florence route?

    Several major train operators run on this route with 1 trains available per day.

  4. What are the earliest and latest departure times for the train from Orlando to Florence?

    The earliest train from Orlando to Florence departs at 13:36. And the latest train departs at 18:50.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/12
£70
11/12
No data
Today
£70
13/12
No data
14/12
£113
15/12
No data
16/12
No data
17/12
No data
busbud logoThe cheapest trip from Orlando to Florence, SC, US was searched and found on 10 Dec 2025 with a price of £70

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Orlando to Florence, SC, US as early as possible.

You can expect to pay from £70 to £355 for a train ticket from Orlando to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £113, which is on 2025-12-14.

What's the cheapest way to go from Orlando to Florence, SC, US?

busbud logoThe train is the cheapest travel choice for this destination

The best way to travel between Orlando and Florence, SC, US is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost £74 on average. If you're on a budget, you'll find cheap tickets from £49. If you're looking for the fastest way to get to Florence, SC, US, choose the train, as it will take you from Orlando to Florence, SC, US in about 9h 35m – that's the fastest way to get there!

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