Find coaches from Orlando to Florence, SC, US

Find affordable coach tickets from Orlando to Florence, SC, US with flexible options. Book your journey now

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Today25 Jun
Tomorrow26 Jun
from US$65
Fri27 Jun
from US$68
Sat28 Jun
Sun29 Jun
from US$72
Mon30 Jun
from US$74
Tue1 Jul
from US$72
Wed2 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 26 June at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 26 June at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Orlando to Florence

Bus
Average priceUS$63 - US$143Average duration10h 5m
16kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$72 - US$215Average duration9h 46m
59kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Orlando to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 10 hours 5 minutes and with fares starting at just US$63, it presents an excellent value for a comfortable ride.

3bus per day
10h 5mAverage duration
US$63Cheapest ticket
16kgCO₂ emissions

Bus Orlando to Florence: Trip Overview

Average ticket priceUS$76
Average bus trip duration10h 5m
Number of daily buses2.2758620689655173
Earliest bus departure04:00
Distance401 miles
Latest bus departure15:40

Orlando to Florence Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Florence.

We make sure you can find a bus service from Orlando to Florence from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Orlando to Florence, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Orlando - Florence, SC, US

  1. What's the distance between Orlando and Florence by coach?

    The journey from Orlando to Florence by coach covers an approximate distance of 405 miles (653 km).

  2. How can I travel from Orlando to Florence avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/06
US$87
24/06
No data
Today
No data
26/06
US$57
27/06
US$60
28/06
No data
29/06
US$64
30/06
US$66
busbud logoThe cheapest trip from Orlando to Florence was searched and found on 26 Jun 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Florence as early as possible.

You can expect to pay from US$57 to US$158 for a bus ticket from Orlando to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$57, which is on 2025-06-26.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Orlando to Florence, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Orlando to Florence that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Orlando to Florence.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Orlando to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Orlando by bus?

Bus from Orlando to Florence

You can also go to Florence by train

Train from Orlando to Florence

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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