Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Bus station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Bus station | Fastest |
Last refresh of the prices: Yesterday at 00:22 EST.
Compare 2 ways to travel from Orlando to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 9 hours 35 minutes and with fares starting at just £45, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Florence?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
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Frequently asked questions about travelling by bus from Orlando to Florence, SC, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Orlando to Florence?
The cheapest coach tickets from Orlando to Florence start from £45. The average price for this route is around £82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Orlando to Florence?
The average bus journey time from Orlando to Florence is 9h 35m, covering a distance of 402 miles. The fastest bus can take you there in 8h 25m and is operated by FlixBus.
Which bus companies service the Orlando to Florence route?
What is the earliest and latest departure time for the bus from Orlando to Florence?
The earliest bus departs from Orlando to Florence at 04:00. And the latest bus departs at 22:55.
What are the CO₂ emissions for the bus trip from Orlando to Florence?
A bus journey from Orlando to Florence produces an estimated 16 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Orlando to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which company has the best Wi-Fi from Orlando to Florence?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Orlando to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Florence, SC, US was searched and found on 6 Dec 2025 with a price of £46To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Florence, SC, US as early as possible.
You can expect to pay from £46 to £166 for a bus ticket from Orlando to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £46, which is on 2025-12-06.
What's the cheapest way to go from Orlando to Florence, SC, US?
The bus is the cheapest travel choice for this destination
