Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Chicago (Union Station), IL | Gateway Station | CheapestFastest | |||||
| Chicago (Union Station), IL | Gateway Station | No tags | |||||
| Chicago (Union Station), IL | Gateway Station | No tags | |||||
| Chicago (Union Station), IL | Gateway Station | No tags | |||||
| Chicago (Union Station), IL | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 23:03 CST.
Compare 2 ways to travel from Chicago to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 5 hours 1 minute and with fares starting at just £23, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Chicago and St. Louis?
Chicago
- A
Union Station
225 S Canal St, Chicago, IL 60606, USA
Train Companies
Customers have shared positive experiences regarding their recent trips. They appreciated the quiet and smooth rides, comfortable seating with ample space to relax or sleep, and efficient senior customer assistance. Additionally, travelers noted that the train was very clean and enjoyed improved food quality compared to previous journeys.
Amtrak Chicago St. Louis recent customer reviews
My trip experience was very quiet and smooth. I was in comfort and had plenty of space where I could relax and get some sleep. My trip was 4 1/2 hours.
Rosemarie H.
Everything was fine, senior customer assistance, smooth ride,nice seating all good
Samuel S.
The trip was the fastest available option. The train was very clean. I like how they announced for people to respect others and keep noise down by using headphones etc. I believe there was Wi-Fi available, I didn’t need though. It was a great Amtrak experience I had compared to my past Amtrak travels, I remember from more than 2-3 years back. The food was also better than I remembered.
Bonnie D.
Frequently asked questions about travelling from Chicago to St. Louis by train
How much does a cheap train ticket from Chicago to St. Louis cost?
The average train ticket price from Chicago to St. Louis is £27. The best way to find cheap train tickets from Chicago to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Chicago to St. Louis?
A train trip between Chicago and St. Louis is around 5h 1m, although the fastest train will take about 4h 46m. This is the time it takes to travel the 260 miles that separates the two cities.
How many daily train are there between Chicago and St. Louis?
The number of trains from Chicago to St. Louis can differ depending on the day of the week. On average, there are 5. Some trains are direct while others include transferring trains. Simplify your train trip from Chicago to St. Louis by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Chicago to St. Louis?
When taking the train from Chicago to St. Louis, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to St. Louis was searched and found on 22 Nov 2025 with a price of £31To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to St. Louis as early as possible.
You can expect to pay from £31 to £382 for a train ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £31, which is on 2025-11-27.
What's the cheapest way to go from Chicago to St. Louis?
The train is the cheapest travel choice for this destinationThe best way to travel between Chicago and St. Louis is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost £27 on average. If you're on a budget, you'll find cheap tickets from £23. If you're looking for the fastest way to get to St. Louis, choose the train, as it will take you from Chicago to St. Louis in about 5h 1m – that's the fastest way to get there!
Top Travelled Train Routes
People from around the world trust Busbud
Popular train departures from Chicago
- Find train tickets from Chicago to Memphis
- Chicago to Kansas City train times and fares
- How to travel from Chicago to Champaign
- Find train tickets from Chicago to Indianapolis
- Chicago to Milwaukee train times and fares
- How to travel from Chicago to Cleveland
- Find train tickets from Chicago to New York City