Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santa Maria Novella | Lyon Part-Dieu | Cheapest | |||||
| Santa Maria Novella | Lyon Part-Dieu | Fastest | |||||
| Santa Maria Novella | Lyon Part-Dieu | No tags |
Last refresh of the prices: Yesterday at 19:52 CET.
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Compare 3 ways to travel from Florence to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 8 hours 20 minutes and with fares starting at just £29, it presents an excellent value for a comfortable ride.
Train Florence to Lyon: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 56 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the departure location but often complained with the Wi-Fi. Trenitalia ticket prices on this trip start at £131
Florence to Lyon Train
With Busbud, comparing and booking tickets for a train from Florence to Lyon is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train services from Florence to Lyon.
Whether it is train tickets or first class train tickets going to Lyon from Florence, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Florence and Lyon?
Frequently asked questions on the trip Florence - Lyon
How much does a cheap train ticket from Florence to Lyon cost?
The average train ticket price from Florence to Lyon is £181. The best way to find cheap train tickets from Florence to Lyon is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Florence to Lyon?
A train trip between Florence and Lyon is around 7h 37m, although the fastest train will take about 7h 37m. This is the time it takes to travel the 343 miles that separates the two cities.
How many daily train are there between Florence and Lyon?
The number of trains from Florence to Lyon can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Florence to Lyon by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Florence to Lyon?
When taking the train from Florence to Lyon, you can travel comfortably and safely with Trenitalia.
What are the departure and arrival stations for a train from Florence to Lyon?
Trains travelling between Florence and Lyon leave from Santa Maria Novella or Florence - Piazzale Montelungo and arrive at Lyon Part-Dieu, Perrache, Lyon Airport.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence to Lyon was searched and found on 5 Nov 2025 with a price of £111To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence to Lyon as early as possible.
You can expect to pay from £111 to £262 for a train ticket from Florence to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at £111, which is on 2025-11-05.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Florence to Lyon is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Lyon, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Florence and Lyon, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Florence to Lyon while indulging in miles on end of beautiful scenic views.
Did you know?
One of the deepest train stations in the world is in Kiev. Located at a depth of 105m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60m under the Great Wall of China!
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.
Top Travelled Train Routes
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