Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Santa Fe Depot | Guadalupe-Santa Maria, CA | Cheapest | ||||
| Train | Old Town San Diego | Guadalupe-Santa Maria, CA | Fastest | ||||
| Train | Old Town San Diego | Guadalupe-Santa Maria, CA | No tags | ||||
| Train | Old Town San Diego | Guadalupe-Santa Maria, CA | No tags | ||||
| Train | Old Town San Diego | Guadalupe-Santa Maria, CA | No tags |
Last refresh of the prices: Yesterday at 00:32 PST.
Get from San Diego to Guadalupe
The journey takes about 7 hours 55 minutes, and with fares starting at just £47, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5593 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at £47
Frequently asked questions about travelling from San Diego, CA, US to Guadalupe, US by train
How much does a cheap train ticket from San Diego to Guadalupe cost?
The average train ticket price from San Diego to Guadalupe is £47. The best way to find cheap train tickets from San Diego to Guadalupe is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from San Diego to Guadalupe?
A train trip between San Diego and Guadalupe is around 7h 55m, although the fastest train will take about 7h 43m. This is the time it takes to travel the 250 miles that separates the two cities.
How many daily train are there between San Diego and Guadalupe?
The number of trains from San Diego to Guadalupe can differ depending on the day of the week. On average, there are 3. Some trains are direct while others include transferring trains. Simplify your train trip from San Diego to Guadalupe by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from San Diego to Guadalupe?
When taking the train from San Diego to Guadalupe, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to Guadalupe, US was searched and found on 17 Nov 2025 with a price of £45To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to Guadalupe, US as early as possible.
You can expect to pay from £45 to £77 for a train ticket from San Diego, CA, US to Guadalupe, US based on the last 2 days. You can expect to find the cheapest price for the trip at £45, which is on 2025-11-21.
