Find coaches from Brindisi to Siena

Previously seen journeys

Next departures from Brindisi to Siena on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Brindisi Bus Stop
    		Piazza GramsciNo tags
    MarinoBus
      		Brindisi Bus Stop
      		Siena Train StationNo tags
      FlixBus
        		Brindisi Bus Stop
        		Piazza GramsciNo tags
        FlixBus
          		Brindisi Bus Stop
          		Viale Toselli (Penny Market)No tags
          FlixBus
            		Brindisi Bus Stop
            		Siena Train StationNo tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to travel from Brindisi to Siena

            We recommend carpooling

            Among the sustainable travel choices, the carpool stands out as a good way to reach Siena. The journey takes about 8 hours 50 minutes and with fares starting at just US$57, it presents an excellent value for a comfortable ride.

            1carpool per day
            8h 50mAverage duration
            623 kmDistance
            26kgCO₂ emissions
            Bus
            		Average priceUS$23 - US$156Average duration12h 34m
            16kg CO₂e
            Carpool
            		Average priceUS$57 - US$57Average duration8h 50m
            26kg CO₂e

            Bus Brindisi to Siena: Trip Overview

            Average ticket priceUS$82
            Average bus trip duration12h 34m
            Number of daily buses10
            Earliest bus departure05:30
            Distance623 km
            Latest bus departure23:30

            Brindisi to Siena Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Brindisi to Siena.

            We make sure you can find a bus service from Brindisi to Siena from the most reliable bus companies operating this trip.

            From cheap bus tickets to more luxurious buses travelling from Brindisi to Siena, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Brindisi - Siena

            1. How much does a bus ticket from Brindisi to Siena cost?

              The bus ticket price from Brindisi to Siena starts at US$23. The best way to find cheap bus tickets from Brindisi to Siena is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Brindisi to Siena?

              The average travel time between Brindisi and Siena is around 12h 34m, although the fastest bus will take about 10h 35m. This is the time it takes to travel the 624 km that separates the two cities.

            3. How many daily bus connections are there between Brindisi and Siena?

              The number of buses from Brindisi to Siena can differ depending on the day of the week. On average, there are 10 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brindisi to Siena by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Brindisi to Siena?

              When taking the bus from Brindisi to Siena, you can travel comfortably and safely with FlixBus, Itabus, MarinoBus.

            5. What are the departure and arrival stations when taking the bus from Brindisi to Siena?

              Buses travelling between Brindisi and Siena leave from Brindisi Bus Stop or Brindisi Airport and arrive at Piazza Gramsci, Via Sallustio Bandini, 21, Via Giuseppe Mazzini, 58.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            31/10
            US$30
            01/11
            No data
            Today
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            03/11
            No data
            04/11
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            05/11
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            06/11
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            07/11
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            busbud logoThe cheapest trip from Brindisi to Siena was searched and found on 31 Oct 2025 with a price of US$30

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brindisi to Siena as early as possible.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Brindisi to Siena but it'll also be endearing to native speakers who will surely appreciate your effort.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Brindisi to Siena, get comfy and count the stars.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Brindisi to Siena that are otherwise impossible to come by with a plane.

            Make a music playlist for your bus ride from Brindisi to Siena, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            Will you be returning to Brindisi by bus?

            Bus from Siena to Brindisi

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