How much is the bus ticket from Brindisi to Siena?

The cheapest bus tickets from Brindisi to Siena start at R 511. The average price for this route is around R 746. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Brindisi to Siena?

The average bus journey time from Brindisi to Siena is 12h, covering a distance of 624 km. The fastest bus gets you there in 10h 35m and is operated by Itabus .

Which bus companies service the Brindisi to Siena route?

Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus , MarinoBus , Itabus .

What is the earliest and latest departure time for the bus from Brindisi to Siena?

The earliest bus departs from Brindisi to Siena at 05:35. And the latest bus departs at 23:30.

What are the CO₂ emissions for the bus trip from Brindisi to Siena?

A bus trip from Brindisi to Siena produces an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Brindisi to Siena?

According to Busbud customers, the highest-rated bus company on this route is MarinoBus , with an average rating of 4.1 out of 5 stars based on 908 reviews.

Which bus company has the best Wi-Fi from Brindisi to Siena?

Based on reviews on Busbud, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.3.

Which bus company offers the most punctual service from Brindisi to Siena?

According to Busbud traveller reviews, the most punctual bus company on this route is MarinoBus , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Brindisi to Siena?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus , with a cleanliness rating of 4.3 out of 5 stars.

Bus Brindisi to Siena from R 450 | Refundable Tickets

Previously seen journeys

Next departures from Brindisi to Siena on 28 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:40	Brindisi Bus Stop	16h 25m	05:05	Siena (Stellino)	No tags
Bus	16:35	Brindisi Bus Stop	15h 45m	08:20	Viale Toselli (Penny Market)	No tags
Bus	21:30	Brindisi Bus Stop	13h	10:30	Siena Train Station	No tags
Bus	23:30	Brindisi Bus Stop	15h 20m	14:50	Viale Toselli (Penny Market)	No tags
Bus	23:30	Brindisi Bus Stop	11h 45m	11:15	Siena Train Station	No tags

Compare 2 ways to travel from Brindisi to Siena

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Siena. The journey takes about 12 hours and with fares starting at just R 511, it presents an excellent value for a comfortable ride.

6bus per day

12hAverage duration

624 kmDistance

16kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 511 - R 1 468	Average duration12h	CO₂ emissions 16kg CO₂e
Carpool	Average priceR 916 - R 916	Average duration8h 50m	CO₂ emissions 26kg CO₂e

Where are the popular stops in Brindisi and Siena?

Stops in Brindisi

A
Brindisi Bus Stop
Via Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
Visit page
B
Brindisi Airport
C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy
D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy
E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy
F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy

Stops in Siena

A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy
Visit page
B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy

Compare bus companies

FlixBus

3.5/512 160 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

MarinoBus

4/5908 reviews

Staff4.7

Timeliness4.3

Cleanliness4.3

WiFi3.3

Itabus

4/5975 reviews

Staff4.3

Timeliness3

Cleanliness4.2

WiFi3.1

IT bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Brindisi to Siena by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Brindisi to Siena?
The cheapest bus tickets from Brindisi to Siena start at R 511. The average price for this route is around R 746. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Brindisi to Siena?
The average bus journey time from Brindisi to Siena is 12h, covering a distance of 624 km. The fastest bus gets you there in 10h 35m and is operated by Itabus.
Which bus companies service the Brindisi to Siena route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, MarinoBus, Itabus.
What is the earliest and latest departure time for the bus from Brindisi to Siena?
The earliest bus departs from Brindisi to Siena at 05:35. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Brindisi to Siena?
A bus trip from Brindisi to Siena produces an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Brindisi to Siena?
According to Busbud customers, the highest-rated bus company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 908 reviews.
Which bus company has the best Wi-Fi from Brindisi to Siena?
Based on reviews on Busbud, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.3.
Which bus company offers the most punctual service from Brindisi to Siena?
According to Busbud traveller reviews, the most punctual bus company on this route is MarinoBus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Brindisi to Siena?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

26/01

No data

27/01

No data

Today

R 470

29/01

R 460

30/01

No data

31/01

No data

01/02

R 665

02/02

No data

The cheapest trip from Brindisi to Siena was searched and found on 29 Jan 2026 with a price of R 460

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brindisi to Siena as early as possible.

You can expect to pay from R 460 to R 1 331 for a bus ticket from Brindisi to Siena based on the last 2 days. You can expect to find the cheapest price for the trip at R 460, which is on 2026-01-29.

Usually MarinoBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.