Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Durham Greyhound Bus Station | Downtown Transit Center | No tags | ||||
| Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags |
Compare 2 ways to travel from Durham to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 22 hours 30 minutes and with fares starting at just R 2 505, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Indianapolis?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about travelling from Durham, NC, US to Indianapolis by bus
How much does a bus ticket from Durham to Indianapolis cost?
The bus ticket price from Durham to Indianapolis starts at R 2 505. The best way to find cheap bus tickets from Durham to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Durham to Indianapolis?
The average travel time between Durham and Indianapolis is around 22h 30m, although the fastest bus will take about 18h 55m. This is the time it takes to travel the 764 km that separates the two cities.
How many daily bus connections are there between Durham and Indianapolis?
The number of buses from Durham to Indianapolis can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Indianapolis by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Durham to Indianapolis?
When taking the bus from Durham to Indianapolis, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Durham to Indianapolis?
Buses travelling between Durham and Indianapolis leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Greyhound Amtrak Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on 20 Nov 2025 with a price of R 3 490To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Indianapolis as early as possible.
What's the cheapest way to go from Durham, NC, US to Indianapolis?
The bus is the cheapest travel choice for this destination
