Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
| Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
 | Bus | Durham Greyhound Bus Station | Downtown Transit Center | No tags |
Last refresh of the prices: Yesterday at 9:37 AM EST.
Compare 2 ways to travel from Durham to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 55 minutes and with fares starting at just R 1 543, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Indianapolis?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
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Frequently asked questions about travelling from Durham, NC, US to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Durham to Indianapolis?
The cheapest bus tickets from Durham to Indianapolis start at R 1 543. The average price for this route is around R 3 869. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Durham to Indianapolis?
The average bus journey time from Durham to Indianapolis is 23h 55m, covering a distance of 762 km. The fastest bus gets you there in 18h 55m and is operated by FlixBus.
Which bus companies service the Durham to Indianapolis route?
What is the earliest and latest departure time for the bus from Durham to Indianapolis?
The earliest bus departs from Durham to Indianapolis at 02:30. And the latest bus departs at 22:05.
What are the CO₂ emissions for the bus trip from Durham to Indianapolis?
A bus trip from Durham to Indianapolis produces an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Durham to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87524 reviews.
Which bus company has the best Wi-Fi from Durham to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Durham to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Durham to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on 05 Mar 2026 with a price of R 3 147To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Indianapolis as early as possible.
You can expect to pay from R 3 147 to R 4 301 for a bus ticket from Durham, NC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 147, which is on 2026-03-05.
