Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags | ||||
| Bus | Durham Greyhound Bus Station | Indianapolis Bus Station | No tags |
Compare 2 ways to go from Durham to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 22 hours 30 minutes, and with fares starting at just $209, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Indianapolis?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
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Frequently asked questions about travelling from Durham, NC, US to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Durham to Indianapolis?
The cheapest bus tickets from Durham to Indianapolis start from $209. The average price for this route is around $306. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Indianapolis?
The average bus travel time from Durham to Indianapolis is 22h 30m, covering a distance of 762 km. The quickest bus can get you there in 18h 55m and is operated by FlixBus.
Which bus companies service the Durham to Indianapolis route?
What are the earliest and latest departure times for the bus from Durham to Indianapolis?
The earliest bus departs from Durham to Indianapolis at 1:10am. And the latest bus departs at 10:05pm.
What are the CO₂ emissions for the bus trip from Durham to Indianapolis?
A bus trip from Durham to Indianapolis generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Durham to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Durham to Indianapolis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Durham to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Durham to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Indianapolis was searched and found on Nov 26, 2025 with a price of $413To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Indianapolis, as early as possible.
What's the cheapest way to go from Durham, NC, US to Indianapolis?
The bus is the cheapest travel choice for this destination
