Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florence (Villa Costanza) | Isernia | No tags | ||||
| Bus | Florence (Villa Costanza) | Isernia | No tags | ||||
| Bus | Florence (Villa Costanza) | Isernia | No tags | ||||
| Bus | Florence (Villa Costanza) | Isernia | No tags | ||||
| Bus | Viale Filippo Strozzi | Isernia | No tags |
Compare 2 ways to travel from Florence to Isernia
Among the sustainable travel choices, the carpool stands out as a good way to reach Isernia. The journey takes about 4 hours and with fares starting at just R 384, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 625 - R 1 974 | Average duration10h 14m | 9kg CO₂e | ||
Carpool | Average priceR 384 - R 764 | Average duration4h | 14kg CO₂e |
Where are the popular stops in Florence and Isernia?
Stops in Florence
- A
Florence - Piazzale Montelungo
50129 Centro Storico FI, Italy - BA1 - Autostrada del Sole, 50018 Scandicci FI, Italy
- DVia della Costituzione, 185, 50018 Scandicci FI, Italy
- EPiazza della Stazione 45, 50123 Firenze, Italy
- FVia Cassia, 49B, 50023 Impruneta FI, Italy
Compare bus companies
Based on 11705 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 625
Frequently asked questions about travelling from Florence to Isernia by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Florence to Isernia?
The cheapest bus tickets from Florence to Isernia start at R 625. The average price for this route is around R 1 044. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Florence to Isernia?
The average bus journey time from Florence to Isernia is 10h 14m, covering a distance of 347 km. The fastest bus gets you there in 6h 55m and is operated by FlixBus.
Which bus companies service the Florence to Isernia route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Isernia?
The earliest bus departs from Florence to Isernia at 01:10. And the latest bus departs at 23:10.
What are the CO₂ emissions for the bus trip from Florence to Isernia?
A bus trip from Florence to Isernia produces an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence to Isernia was searched and found on 22 Dec 2025 with a price of R 839To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Isernia as early as possible.
