Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Tupelo (Brothers Quick Stop) | CheapestFastest | ||||
 | Bus | Gainesville Bus Stop | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Tupelo (Brothers Quick Stop) | No tags |
Last refresh of the prices: Today at 12:23 AM EST.
Get from Gainesville to Tupelo
The journey takes about 14 hours 5 minutes, and with fares starting at just R 2 187, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 2 237
Frequently asked questions about travelling from Gainesville, FL to Tupelo by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Gainesville to Tupelo?
The cheapest bus tickets from Gainesville to Tupelo start at R 2 187. The average price for this route is around R 2 261. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Gainesville to Tupelo?
The average bus journey time from Gainesville to Tupelo is 14h 5m, covering a distance of 788 km. The fastest bus gets you there in 14h 5m and is operated by Greyhound.
Which bus companies service the Gainesville to Tupelo route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Gainesville to Tupelo?
The earliest bus departs from Gainesville to Tupelo at 01:10. And the latest bus departs at 21:20.
What are the CO₂ emissions for the bus trip from Gainesville to Tupelo?
A bus trip from Gainesville to Tupelo produces an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Tupelo was searched and found on 01 Feb 2026 with a price of R 2 863To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Tupelo as early as possible.
You can expect to pay from R 2 863 to R 2 863 for a bus ticket from Gainesville, FL to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 863, which is on 2026-02-01.
