Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Gray & Smith | Lake City Bus Station | Cheapest | ||||
 | Bus | Houston Lockwood, (TX - TBC Lockwood) | Lake City Bus Stop | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | Lake City Bus Station | No tags | ||||
 | Bus | Houston Bus Station | Lake City Bus Station | No tags | ||||
| Bus | Houston Lockwood, (TX - TBC Lockwood) | Lake City Bus Stop | No tags |
Last refresh of the prices: Today at 4:13 AM CST.
Get from Houston to Lake City
The journey takes about 19 hours 25 minutes, and with fares starting at just R 2 874, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Lake City?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
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Frequently asked questions about travelling from Houston, US to Lake City by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Houston to Lake City?
The cheapest bus tickets from Houston to Lake City start at R 2 874. The average price for this route is around R 3 669. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Houston to Lake City?
The average bus journey time from Houston to Lake City is 19h 25m, covering a distance of 1221 km. The fastest bus gets you there in 13h and is operated by Tornado Bus.
Which bus companies service the Houston to Lake City route?
Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, Tornado Bus, FlixBus.
What is the earliest and latest departure time for the bus from Houston to Lake City?
The earliest bus departs from Houston to Lake City at 05:00. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Houston to Lake City?
A bus trip from Houston to Lake City produces an estimated 31 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Houston to Lake City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Houston to Lake City?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Houston to Lake City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Lake City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Lake City was searched and found on 15 Dec 2025 with a price of R 2 594To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Lake City as early as possible.
You can expect to pay from R 2 594 to R 3 200 for a bus ticket from Houston, US to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 594, which is on 2025-12-15.
