Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Karlsruhe | Estación Sur | CheapestFastest | |||||
| Karlsruhe | Estación Sur | No tags |
Last refresh of the prices: Yesterday at 6:42 PM CET.
Compare 2 ways to travel from Karlsruhe to Madrid
Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 18 hours 50 minutes and with fares starting at just R 2 913, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 1 352 - R 5 393 | Average duration1d 3h | 34kg CO₂e | ||
Carpool | Average priceR 2 913 - R 2 913 | Average duration18h 50m | 57kg CO₂e |
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Where are the popular stops in Karlsruhe and Madrid?
Frequently asked questions about travelling from Karlsruhe to Madrid by bus
How much does a bus ticket from Karlsruhe to Madrid cost?
The bus ticket price from Karlsruhe to Madrid starts at R 1 352. The best way to find cheap bus tickets from Karlsruhe to Madrid is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Karlsruhe to Madrid?
The average travel time between Karlsruhe and Madrid is around 1d 3h, although the fastest bus will take about 1d 1h. This is the time it takes to travel the 1350 km that separates the two cities.
How many daily bus connections are there between Karlsruhe and Madrid?
The number of buses from Karlsruhe to Madrid can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Karlsruhe to Madrid by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Karlsruhe to Madrid?
When taking the bus from Karlsruhe to Madrid, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Karlsruhe to Madrid?
Buses travelling between Karlsruhe and Madrid leave from Südseite Hauptbahnhof or Karlsruhe Hbf and arrive at Estación Sur, Madrid-Barajas Airport, Avenida de América Metro.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Madrid was searched and found on 21 Nov 2025 with a price of R 1 260To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Madrid as early as possible.
You can expect to pay from R 1 260 to R 3 629 for a bus ticket from Karlsruhe to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 260, which is on 2025-11-21.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Karlsruhe to Madrid?
The bus is the cheapest travel choice for this destination
