Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Key West Bus Station | Rosa Parks Station | Cheapest | ||||
 | Bus | Key West Bus Station | Gainesville Bus Stop | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Key West Bus Station | Rosa Parks Station | No tags |
Last refresh of the prices: Today at 11:14 AM EDT.
Get from Key West to Gainesville
The journey takes about 15 hours 5 minutes, and with fares starting at just MAD 1 098, it presents an excellent value for a comfortable ride.
Bus stations and stops in Key West and Gainesville
Stops in Key West
- A
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA - B
Caroline St
908 Caroline St, Key West, FL 33040, USA
Stops in Gainesville
- A
Rosa Parks Station
700 SE 3rd St, Gainesville, FL 32601 - B
Williston Rd & I-75
3509 SW Williston Rd, Gainesville, FL 32608, USA - C
Greyhound Station
101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Based on 87585 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at MAD 1 132
Frequently asked questions about travelling from Key West to Gainesville, FL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Key West to Gainesville?
The cheapest bus tickets from Key West to Gainesville start at MAD 1 098. The average price for this route is around MAD 1 132. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Key West to Gainesville?
The average bus journey time from Key West to Gainesville is 15h 5m, covering a distance of 570 km. The fastest bus gets you there in 14h 50m and is operated by Greyhound.
Which bus companies service the Key West to Gainesville route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Key West to Gainesville?
The earliest bus departs from Key West to Gainesville at 10:00. And the latest bus departs at 17:00.
What are the CO₂ emissions for the bus trip from Key West to Gainesville?
A bus trip from Key West to Gainesville produces an estimated 14.226824999999998 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Key West to Gainesville, FL was searched and found on 22 Jul 2026 with a price of MAD 743To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to Gainesville, FL as early as possible.
You can expect to pay from MAD 743 to MAD 743 for a bus ticket from Key West to Gainesville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at MAD 743, which is on 2026-07-22.
