Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mainz | Perrache | No tags | ||||
| Bus | Mainz | Aéroport LYS | No tags | ||||
| Bus | Mainz | Perrache | No tags | ||||
| Bus | Mainz | Aéroport LYS | No tags | ||||
| Bus | Mainz | Lyon | No tags |
Compare 2 ways to travel from Mainz to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 6 hours 50 minutes and with fares starting at just R 1 244, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 832 - R 2 399 | Average duration17h 5m | 13kg CO₂e | ||
Carpool | Average priceR 1 244 - R 1 244 | Average duration6h 50m | 22kg CO₂e |
Where are the popular stops in Mainz and Lyon?
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz - Cflibco.com bus stop, Kaiser-Wilhelm-Ring, 55118 Mainz, Germany
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- B
Lyon Airport
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Based on 11646 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 832
Frequently asked questions about travelling from Mainz to Lyon by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mainz to Lyon?
The cheapest bus tickets from Mainz to Lyon start at R 832. The average price for this route is around R 1 414. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mainz to Lyon?
The average bus journey time from Mainz to Lyon is 17h 5m, covering a distance of 538 km. The fastest bus gets you there in 10h 35m and is operated by FlixBus.
Which bus companies service the Mainz to Lyon route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Mainz to Lyon?
The earliest bus departs from Mainz to Lyon at 01:00. And the latest bus departs at 22:40.
What are the CO₂ emissions for the bus trip from Mainz to Lyon?
A bus trip from Mainz to Lyon produces an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Lyon was searched and found on 20 Dec 2025 with a price of R 1 178To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Lyon as early as possible.
You can expect to pay from R 1 178 to R 2 335 for a bus ticket from Mainz to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 178, which is on 2025-12-20.
