Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mainz | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Cheapest | ||||
| Bus | Mainz | Madrid (South) | Fastest | ||||
| Bus | Mainz | Madrid (South) | No tags | ||||
| Bus | Mainz | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | No tags |
Last refresh of the prices: Yesterday at 12:51 PM CET.
Get from Mainz to Madrid
The journey takes about 1 day, 7 hours 40 minutes, and with fares starting at just R 2 441, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mainz and Madrid?
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz - Cflibco.com bus stop, Kaiser-Wilhelm-Ring, 55118 Mainz, Germany
Stops in Madrid
- BMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Compare bus companies
Based on 11998 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 2 441
Frequently asked questions about travelling from Mainz to Madrid by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mainz to Madrid?
The cheapest bus tickets from Mainz to Madrid start at R 2 441. The average price for this route is around R 3 083. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mainz to Madrid?
The average bus journey time from Mainz to Madrid is 1d 7h, covering a distance of 1404 km. The fastest bus gets you there in 1d 4h and is operated by FlixBus.
Which bus companies service the Mainz to Madrid route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Mainz to Madrid?
The earliest bus departs from Mainz to Madrid at 01:00. And the latest bus departs at 22:40.
What are the CO₂ emissions for the bus trip from Mainz to Madrid?
A bus trip from Mainz to Madrid produces an estimated 35 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Madrid was searched and found on 11 Jan 2026 with a price of R 2 076To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Madrid as early as possible.
