Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Messina Centrale | Ascoli Piceno | CheapestFastest |
Last refresh of the prices: Last Thursday at 12:24 PM CET.
Get from Messina to Ascoli Piceno
The journey takes about 21 hours 20 minutes, and with fares starting at just R 1 269, it presents an excellent value for a comfortable ride.
Where are the popular stops in Messina and Ascoli Piceno?
Stops in Messina
- APiazza Stazione, 98122 Messina ME, Italy
- B
Piazza della Repubblica
Via Guido delle Colonne, 49, 98122 Messina ME, Italy - C
Via Giuseppe Garibaldi 263
Via Giuseppe Garibaldi 263, 98122 Messina ME, Italy - D
Porto
Capitaneria di Porto, Via Vittorio Emanuele II, 111, 98100 Messina ME, Italy
Compare bus companies
Based on 12141 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 269
Frequently asked questions about travelling from Messina to Ascoli Piceno by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Messina to Ascoli Piceno?
The cheapest bus tickets from Messina to Ascoli Piceno start at R 1 269. The average price for this route is around R 1 269. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Messina to Ascoli Piceno?
The average bus journey time from Messina to Ascoli Piceno is 21h 20m, covering a distance of 546 km. The fastest bus gets you there in 21h 20m and is operated by FlixBus.
Which bus companies service the Messina to Ascoli Piceno route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Messina to Ascoli Piceno?
The earliest bus departs from Messina to Ascoli Piceno at 21:30. And the latest bus departs at 21:30.
What are the CO₂ emissions for the bus trip from Messina to Ascoli Piceno?
A bus trip from Messina to Ascoli Piceno produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Messina to Ascoli Piceno was searched and found on 26 Jan 2026 with a price of R 881To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Messina to Ascoli Piceno as early as possible.
You can expect to pay from R 881 to R 1 821 for a bus ticket from Messina to Ascoli Piceno based on the last 2 days. You can expect to find the cheapest price for the trip at R 881, which is on 2026-01-26.
