Find coaches from Milano to Isernia

Next departures

Next departures from Milano to Isernia on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Milan (Malpensa Aeroporto Terminal 1)
IserniaCheapest
Flixbus
Lampugnano bus station
IserniaFastest
Flixbus
Lampugnano bus station
IserniaNo tags
Flixbus
Milan (San Donato M3)
IserniaNo tags
Flixbus
Milan (San Donato M3)
IserniaNo tags

Last refresh of the prices: Yesterday at 1:31 AM CET.

Accepted payments

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Compare 2 ways to travel from Milano to Isernia

busbud logoWe recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Isernia. The journey takes about 6 hours 50 minutes and with fares starting at just US$49, it presents an excellent value for a comfortable ride.

2carpool per day
6h 50mAverage duration
592 kmDistance
25kgCO₂ emissions
Bus
Average priceUS$57 - US$138Average duration17h 44m
16kg CO₂e
Carpool
Average priceUS$49 - US$63Average duration6h 50m
25kg CO₂e

Bus Milano to Isernia: Trip Overview

Average ticket priceUS$87
Average bus trip duration17h 44m
Number of daily buses10
Earliest bus departure02:25
Distance631 km
Latest bus departure23:10

Milano to Isernia Bus

Busbud helps you find a bus from Milano to Isernia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Milano to Isernia will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Milano to Isernia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Milano - Isernia

  1. How much does a bus ticket from Milano to Isernia cost?

    The bus ticket price from Milano to Isernia starts at US$57. The best way to find cheap bus tickets from Milano to Isernia is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Milano to Isernia?

    The average travel time between Milano and Isernia is around 17h 44m, although the fastest bus will take about 13h 24m. This is the time it takes to travel the 593 km that separates the two cities.

  3. How many daily bus connections are there between Milano and Isernia?

    The number of buses from Milano to Isernia can differ depending on the day of the week. On average, there are 10 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Milano to Isernia by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Milano to Isernia?

    When taking the bus from Milano to Isernia, you can travel comfortably and safely with FlixBus.

  5. What are the departure and arrival stations when taking the bus from Milano to Isernia?

    Buses travelling between Milano and Isernia leave from Linate Airport or Lampugnano and arrive at Isernia.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
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29/10
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Today
US$78
31/10
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01/11
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02/11
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03/11
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04/11
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busbud logoThe cheapest trip from Milano to Isernia was searched and found on 30 Oct 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Isernia as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Isernia!

Much more than a mere vehicle taking you from Milano to Isernia, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Milano to Isernia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Milano to Isernia while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Milano by bus?

Bus from Isernia to Milano

Why choose Busbud?

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