Next bus departures

Next departures from Naples to Indianapolis on 9 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 12h	08:00	Indianapolis (W Vermont St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	13:20	11555 Bonita Beach Rd (Bonita Spring)	1d 3h	16:45	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 9h	04:55	Indianapolis Bus Station	No tags
	Bus	13:20	11555 Bonita Beach Rd (Bonita Spring)	1d 8h	21:45	Indianapolis (W Vermont St)	No tags

Next departures from Naples to Indianapolis on 10 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	13:20	11555 Bonita Beach Rd (Bonita Spring)	1d 8h	21:45	Indianapolis (W Vermont St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	13:20	11555 Bonita Beach Rd (Bonita Spring)	1d 3h	16:45	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 9h	04:55	Indianapolis Bus Station	No tags

Next departures from Naples to Indianapolis on 11 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 6h	16:45	Indianapolis Bus Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 9h	04:55	Indianapolis Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 11h	21:45	Indianapolis (W Vermont St)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 12h	08:00	Indianapolis (W Vermont St)	No tags

Next departures from Naples to Indianapolis on 12 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	17:40	11555 Bonita Beach Rd (Bonita Spring)	1d 14h	08:00	Indianapolis (W Vermont St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 6h	16:45	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	17:40	11555 Bonita Beach Rd (Bonita Spring)	1d 11h	04:55	Indianapolis Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 11h	21:45	Indianapolis (W Vermont St)	No tags

Next departures from Naples to Indianapolis on 14 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 12h	08:00	Indianapolis (W Vermont St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 6h	16:45	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	19:30	11555 Bonita Beach Rd (Bonita Spring)	1d 9h	04:55	Indianapolis Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	09:50	11555 Bonita Beach Rd (Bonita Spring)	1d 11h	21:45	Indianapolis (W Vermont St)	No tags

Last refresh of the prices: Last Friday at 6:20 PM EDT.

Get from Naples to Indianapolis

This route is served by bus only

The journey takes about 1 day, 9 hours 25 minutes, and with fares starting at just CA$184, it presents an excellent value for a comfortable ride.

4bus per day

1d 9hAverage duration

1549 kmDistance

39kgCO₂ emissions

Bus stations and stops in Naples and Indianapolis

Stops in Naples

A
Pine Ridge & I-75
6065 Pine Ridge Rd (McDonald's), Naples, FL 34102
B
Naples, FL
8875 Davis Blvd (McDonald's, I-75 S Exit 101), Naples, FL 33962

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
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Compare bus companies

FlixBus

3.5/515 039 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

WiFi2.7

Based on 15039 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. FlixBus ticket prices on this trip start at CA$191

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about travelling from Naples, FL, US to Indianapolis by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Naples to Indianapolis?
The cheapest bus tickets from Naples to Indianapolis start at CA$184. The average price for this route is around CA$219. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Naples to Indianapolis?
The average bus journey time from Naples to Indianapolis is 1d 9h, covering a distance of 1549 km. The fastest bus gets you there in 1d 8h and is operated by FlixBus.
Which bus companies service the Naples to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Naples to Indianapolis?
The earliest bus departs from Naples to Indianapolis at 13:20. And the latest bus departs at 19:30.
What are the CO₂ emissions for the bus trip from Naples to Indianapolis?
A bus trip from Naples to Indianapolis produces an estimated 38.7166 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/08

CA$324

08/08

CA$346

Today

CA$321

10/08

CA$221

11/08

No data

12/08

No data

13/08

No data

14/08

No data

The cheapest trip from Naples, FL, US to Indianapolis was searched and found on 10 Aug 2026 with a price of CA$221

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Naples, FL, US to Indianapolis as early as possible.

You can expect to pay from CA$221 to CA$346 for a bus ticket from Naples, FL, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at CA$221, which is on 2026-08-10.