Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Cross Border Xpress CBX (USA) | Santa Fe Speedway Gas Station | Cheapest | ||||
| Bus | Cross Border Xpress CBX (USA) | Santa Fe Speedway Gas Station | Fastest | ||||
| Bus | Cross Border Xpress CBX (USA) | Santa Fe Speedway Gas Station | No tags | ||||
| Bus | Cross Border Xpress CBX (USA) | Santa Fe Speedway Gas Station | No tags |
Last refresh of the prices: Yesterday at 11:39 AM PST.
Get from San Diego to Santa Fe
The journey takes about 1 day, 3 hours 10 minutes, and with fares starting at just R 3 989, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Diego and Santa Fe?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Stops in Santa Fe
- ASanta Fe Amtrak Station, Santa Fe, NM 87501, USA
- BSanta Fe Amtrak Bus Stop, New Mexico 87506, USA
Compare bus companies
Based on 277 reviews, the company was rated 3.4 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. Los Limousines ticket prices on this trip start at R 3 989
Frequently asked questions about travelling from San Diego, CA, US to Santa Fe, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from San Diego to Santa Fe?
The cheapest bus tickets from San Diego to Santa Fe start at R 3 989. The average price for this route is around R 4 358. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from San Diego to Santa Fe?
The average bus journey time from San Diego to Santa Fe is 1d 3h, covering a distance of 1071 km. The fastest bus gets you there in 1d 1h and is operated by Los Limousines.
Which bus companies service the San Diego to Santa Fe route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from San Diego to Santa Fe?
The earliest bus departs from San Diego to Santa Fe at 10:30. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from San Diego to Santa Fe?
A bus trip from San Diego to Santa Fe produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to Santa Fe, US was searched and found on 14 Dec 2025 with a price of R 3 935To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Santa Fe, US as early as possible.
You can expect to pay from R 3 935 to R 3 956 for a bus ticket from San Diego, CA, US to Santa Fe, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 956, which is on 2025-12-18.
