Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Greenville Station | Union Station | CheapestFastest | |||||
| Greenville Station | Union Station | No tags |
Last refresh of the prices: Today at 3:52 PM EDT.
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Compare 2 ways to travel from Greenville to Pittsburgh
Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 18 hours and with fares starting at just US$90, it presents an excellent value for a comfortable ride.
Train Greenville, SC to Pittsburgh: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5557 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$193
Greenville to Pittsburgh Train
Busbud shows you the best train ticket fares and train schedules so you can plan and book a trip by train easily from Greenville to Pittsburgh.
We make sure you can find a train service from Greenville to Pittsburgh from the most reliable train companies operating this trip.
Discover how much the train trip from Greenville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions on the trip Greenville, SC - Pittsburgh
How much does a cheap train ticket from Greenville to Pittsburgh cost?
The average train ticket price from Greenville to Pittsburgh is US$247. The best way to find cheap train tickets from Greenville to Pittsburgh is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Greenville to Pittsburgh?
A train trip between Greenville and Pittsburgh is around 21h 17m, although the fastest train will take about 21h 17m. This is the time it takes to travel the 657 km that separates the two cities.
How many daily train are there between Greenville and Pittsburgh?
The number of trains from Greenville to Pittsburgh can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Greenville to Pittsburgh by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Greenville to Pittsburgh?
When taking the train from Greenville to Pittsburgh, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Pittsburgh was searched and found on 29 Oct 2025 with a price of US$210To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Pittsburgh as early as possible.
You can expect to pay from US$210 to US$828 for a train ticket from Greenville, SC to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at US$210, which is on 2025-11-01.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Greenville and Pittsburgh is also a great way to travel to arrive in the city centre and save more time for your stay in Pittsburgh.
Regional train? High-speed train? Whichever train to Pittsburgh you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
With up to 30x less CO2 emissions for your train journey between Greenville and Pittsburgh, the train is an ecological alternative to flights or personal cars.
Create your own real-life musical score by curating a personalised train travel playlist – the perfect accompaniment for your journey from Greenville to Pittsburgh.
Did you know?
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.
Japanese trains are always on time. It is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologise to each passenger.
Top Travelled Train Routes
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