Find coaches from Greenville, SC to Pittsburgh

Next departures

Next departures from Greenville to Pittsburgh on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
1116 Woodruff Rd
Pittsburgh Intermodal StationCheapestFastest
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Pittsburgh Intermodal StationNo tags
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Pittsburgh Intermodal StationNo tags

Last refresh of the prices: Yesterday at 10:03 AM EDT.

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Compare 2 ways to travel from Greenville to Pittsburgh

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 18 hours and with fares starting at just US$90, it presents an excellent value for a comfortable ride.

2bus per day
18hAverage duration
657 kmDistance
16kgCO₂ emissions
Bus
Average priceUS$90 - US$206Average duration18h
16kg CO₂e
Train
Average priceUS$193 - US$884Average duration21h 17m
60kg CO₂e

Bus Greenville, SC to Pittsburgh: Trip Overview

Average ticket priceUS$125
Average bus trip duration18h
Number of daily buses2
Earliest bus departure10:50
Distance657 km
Latest bus departure22:00

Greenville to Pittsburgh Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Pittsburgh.

We make sure you can find a bus service from Greenville to Pittsburgh from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Pittsburgh

  1. How much does a bus ticket from Greenville to Pittsburgh cost?

    The bus ticket price from Greenville to Pittsburgh starts at US$90. The best way to find cheap bus tickets from Greenville to Pittsburgh is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Greenville to Pittsburgh?

    The average travel time between Greenville and Pittsburgh is around 18h, although the fastest bus will take about 17h 5m. This is the time it takes to travel the 657 km that separates the two cities.

  3. How many daily bus connections are there between Greenville and Pittsburgh?

    The number of buses from Greenville to Pittsburgh can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Greenville to Pittsburgh by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Greenville to Pittsburgh?

    When taking the bus from Greenville to Pittsburgh, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Greenville to Pittsburgh?

    Buses travelling between Greenville and Pittsburgh leave from Guadalajara Supermarket Bus Stop or Greenville Bus Station and arrive at Intermodal Station, Sennott Square.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
US$123
30/10
No data
Today
US$103
01/11
No data
02/11
No data
03/11
No data
04/11
No data
05/11
No data
busbud logoThe cheapest trip from Greenville, SC to Pittsburgh was searched and found on 31 Oct 2025 with a price of US$103

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Pittsburgh, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Pittsburgh will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Pittsburgh.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Greenville, SC to Pittsburgh?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Pittsburgh to Greenville, SC

You can also go to Pittsburgh by train

Train from Greenville, SC to Pittsburgh

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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