Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Debrecen | Tomíčkova | Cheapest | ||||
| Bus | Debrecen | Prague (Main Railway Station) | Fastest | ||||
| Bus | Debrecen | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Today at 10:42 AM CEST.
Get from Debrecen to Prague
The journey takes about 19 hours 40 minutes and with fares starting at just COP 208,988, it presents an excellent value for a comfortable ride.
Where are the popular stops in Debrecen and Prague?
Stops in Prague
- A
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - B
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Debrecen to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Debrecen to Prague?
The cheapest bus tickets from Debrecen to Prague start from COP 208,988. The average price for this route is around COP 264,102. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Debrecen to Prague?
The average bus trip duration from Debrecen to Prague is 19h 40m, covering a distance of 371 miles (598 km). The quickest bus can get you there in 15h 55m and is operated by FlixBus.
Which bus companies service the Debrecen to Prague route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Debrecen to Prague?
The earliest bus departs from Debrecen to Prague at 6:45pm. And the latest bus departs at 6:45pm.
What are the CO₂ emissions for the bus trip from Debrecen to Prague?
A bus trip from Debrecen to Prague generates an estimated 14.925375 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Debrecen to Prague was searched and found on Jun 15, 2026 with a price of COP 195,940To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Debrecen to Prague, as early as possible.
You can expect to pay from COP 195,940 to COP 277,221 for a bus ticket from Debrecen to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at COP 204,944 which is on 2026-06-18.
